Results 91 to 100 of about 135,490 (305)

Perlindungan Hukum Terhadap Merek Terkenal Dari Tindakan Passing Off Berdasarkan Undang-undang Nomor 15 Tahun 2001 Tentang Merek [PDF]

, 2014
Developments and advances in the field of economics, mainly trade in goods and services had a positive impact and negative for the world in the field of industrial intellectual property rights, especially in the field of trademark. The influx of economic
Firdaus, F. (Firdaus), Hendra, R. (Rahmad), Samariadi, S. (Samariadi)   +2 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Perlindungan Hukum Franchisor Dan Franchisee Dalam Perjanjian Waralaba “Soto Segeer Mbok Giyem” Boyolali [PDF]

, 2016
This study aimed to determine the form of legal protection for trademark holders to the culinary business in Indonesia and the reasons a franchiseein the franchise agreementon" Soto SEGEER mBok Giyem " did not get a legal protection.
RizkiNurAnnisa, R. (RizkiNurAnnisa), Sulistiyono, A. (Adi)   +1 more
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

TINJAUAN YURIDIS TERHADAP KEDUDUKAN HUKUM DAN PERLINDUNGAN HAK ATAS MEREK TERDAFTAR YANG MEMILIKI PERSAMAAN PADA POKOKNYA [PDF]

Registration of a trademark must be based on good faith. If the registration of a trademark is not based on good faith, it will give rise to trademark disputes. Most trademark disputes arise because there are elements of similarity in essence.
Muhammadin, Fourizky Nur
core  

It Depends on What the Meaning of False is: Falsity and Misleadingness in Commercial Speech Doctrine [PDF]

, 2007
While scholarship regarding the Supreme Court\u27s noncommercial speech doctrine has often focused on the level of protection for truthful, non-misleading commercial speech, scholars have paid little attention to the exclusion of false or misleading ...
Tushnet, Rebecca
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Unfair Competition and Uncommon Sense [PDF]

, 2010
This article discusses Mark McKenna’s Testing Modern Trademark Law’s Theory of Harm as an important step forward in challenging trademark expansionism, going back to basics and asking us to assess for truth value several propositions that now seem so ...
Tushnet, Rebecca
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source