Results 41 to 50 of about 135,890 (304)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
For the Love of the Name: Professional Athletes Seek Trademark Protection [PDF]
, 2012 Brett Pavony & Jaia Thomas wrote an article that explores the burgeoning relationship between professional sports and trademark law. After providing an overview of the various requirements outlined by the United States Patent and Trademark Office (USPTO),
Pavony, Brett Harris, Thomas, Jaia
core +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The Role of Trademark Law System in Protecting Fictional Characters: A Focus on the Legal System of the United States of America [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i KhuṣūṣīAs cultural, artistic, and media constructs, fictional characters occupy a special and increasingly important place in today’s intellectual property rights system. These characters—created in the form of fictional works, films, animations, computer games,
Mehdi Zahedi, Sara Solhchi
doaj +1 more source
Study and ranking the Indexes of Legal-Rightprotection policies of industrial property rights with a focus on entrepreneurship development. (Case study: Entrepreneurs of Tehran city) [PDF]
مدیریت بهره وری, 2019 The aim of this study was to Study and ranking the Indexes of Legal-Right protection policies of industrial property rights with a focus on entrepreneurship development. The method of this study was survey and the questionnaire was used.
emeliya ghorbani siavoshani +4 more
doaj +1 more source
Pelaksanaan Prinsip First To File dalam Penyelesaian Sengketa Merek Dagang Asing di Pengadilan (Studi Kasus Tentang Gugatan Pencabutan Hak Merek “Toast Box” oleh Breadtalk Pte.ltd No: 02/merek/2011/pn.niaga/medan) [PDF]
, 2015 The registration of trademark done by the Directorate General of Intellectual PropertyRights was intended to obtaine legal certainty and legal protection for the right to trademark in accordance with Law No.15/2001. The registration of trademark through
SITEPU, V. I. (VANIA)
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source