Viral Pathogens and Pulmonary Fibrosis: EMT-Driven Mechanisms and Insights From Traditional Chinese Medicine. [PDF]
Zang N +9 more
europepmc +1 more source
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
GastroTCM: a large language model assistant for gastroenterology in traditional Chinese medicine. [PDF]
Wang L +10 more
europepmc +1 more source
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun +19 more
wiley +1 more source
Thinking about translational medicine and traditional Chinese medicine
Zhang Boli, Zhang Junhua, Hu Jingqing
doaj +1 more source
Multi-origin analysis of the traditional Chinese medicine Leiwan. [PDF]
Zhang WH +8 more
europepmc +1 more source
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
Regulatory effects of traditional Chinese medicine on the breast-cancer immune microenvironment. [PDF]
Liu T +7 more
europepmc +1 more source
Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu +9 more
wiley +1 more source
The Role of Long Non-Coding RNA in Atherosclerosis: Mechanism and Intervention of Traditional Chinese Medicine. [PDF]
Yang D, Wei J, Lin W, Feng L, Tuo Q.
europepmc +1 more source

