Results 21 to 30 of about 356,588 (263)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Guidelines of Integrated Traditional Chinese and Western Medicine for Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (2025 Edition) [PDF]
Zhongguo quanke yixueChronic obstructive pulmonary disease(COPD) poses a serious threat to human health, making it one of the major global public health burdens. In 2023, an expert consensus group was established to address key clinical questions in the integrated Chinese ...
Guideline Working Group of Integrated Traditional Chinese and Western Medicine Management for Chronic Obstructive Pulmonary Disease
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Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
ON RELATIVE SPECIFICITY OF ACUPOINTS
针刺研究, 1985 From the histological and pathological reactions and electrical characteri- stic sof acupoints as well as their effects on the functions of various organs, the author in accordance with a lot of clinical and experimental materal, has demostrated that ...
Chen Keqin Shaanxi Academy of Traditional Chinese Medicine
doaj
Traditional Chinese medicine phenomics: data characteristics and prospect of research methods
生物医学转化, 2022 Human phenomics constructs the association of cross-scale-omics data, which is of great value to the realization of precision medicine. Both TCM and phenomics focus on the variation patterns of various phenotypes in the complex system of human body, and ...
Zuo Ling, Chen Jianxin
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Classification of interventions in Traditional Chinese Medicine
Journal of Traditional Chinese Medicine, 2018 To describe the key systems used for Traditional Chinese Medicine (TCM) classification.The TCM classifications used in the International Classification of Diseases-9 Clinical Modification (ICD-9-CM) volume 3, the ICD-10 Procedure Coding System, the International Classification of Health Interventions, and the Medical Subject Headings (MeSH) and Chinese
Deng, Hongyong +3 more
openaire +4 more sources