Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Protocol for Systematic Review of Controlled Trials of Korean and Chinese Herbal Treatments for Stroke [PDF]
Background Many stroke patients receive traditional medical care in Korea and China. Stroke patients comprise the largest proportion of inpatients in traditional Korean medicine and traditional Chinese medicine hospitals.
Ju-Ah Lee+7 more
doaj +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
Comparative Study of Traditional Chinese Medicine and Indian Traditional Medicine from the Perspective of International Development [PDF]
Traditional Chinese medicine (TCM) is an important part of Chinese traditional culture. It's also an important health resource, economic resource, technological resource, cultural resource and ecological resource in our country.
CHEN Ying, ZHOU Shuduo, YANG Jian, HU Yunxuan, FENG Xiangning, XU Ming
doaj +1 more source
Multiple Attentional Pyramid Networks for Chinese Herbal Recognition [PDF]
Chinese herbs play a critical role in Traditional Chinese Medicine. Due to different recognition granularity, they can be recognized accurately only by professionals with much experience. It is expected that they can be recognized automatically using new techniques like machine learning.
arxiv
MedChatZH: a Better Medical Adviser Learns from Better Instructions [PDF]
Generative large language models (LLMs) have shown great success in various applications, including question-answering (QA) and dialogue systems. However, in specialized domains like traditional Chinese medical QA, these models may perform unsatisfactorily without fine-tuning on domain-specific datasets.
arxiv
Traditional Chinese Medicine and Colorectal Cancer: Implications for Drug Discovery
As an important part of complementary and alternative medicine, traditional Chinese medicine (TCM) has been applied to treat a host of diseases for centuries.
Qiang Sun+9 more
semanticscholar +1 more source
Traditional Chinese medicine compound Erxian soup extract with menopausal cognitive function [PDF]
The invention relates to modern pharmacology research in traditional Chinese medicines, in particular to a traditional Chinese medicine compound Erxian soup extract with a menopausal cognitive function.
core
A discussion of covid-19 vaccine in relation with traditional chinese medicine belief on weibo [PDF]
Traditional Chinese medicine has been influencing Chinese people for thousands of years. Vaccine, as a means of western medicine, has been on the controversial side of traditional Chinese medicine.
Wang, Yiyi
core +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source