Results 81 to 90 of about 4,973 (251)

The Correlation Study between Traditional Chinese Medicine Constitutions and Immunology

Immunology Studies, 2014
中医体质学是以中医理论为指导，研究人类体质特征、体质类型的生理病理特点，和阐述人体体质与疾病、防治及养生及分析疾病反应状态、病变性质、发展趋向的学科，是一门从宏观辨证研究人体控制系统平衡与失衡及调控，与传统科学相结合的交叉性、应用性学科。免疫学是从微观、定量研究疾病本质，机体的防御、自稳和免疫监视功能的正常与否及其对疾病发生、类别、治疗关系的学科。我们旨在研究中医体质学与免疫学内在规律的本质，期冀努力探索更多免疫调节中草药改善机体免疫状态，为中西医结合理论在实践基础上的结合产生质的飞跃。Traditional Chinese Medicine Constitutions is based on physical science theory, to study the human physical ...
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Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Integrating Traditional Medicine to Improve the Care of Persistent Physical Symptom

Health Care Science
Persistent physical symptom (PPS) is a common condition in sub‐healthy population and patients with chronic disease, and significantly influences the quality of life.
Huai‐Yu Wang, Ji Wang, Qi Wang
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PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
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“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

Multi-omics and machine learning identify novel biomarkers and therapeutic targets of COVID-19

Frontiers in Immunology
IntroductionCOVID-19 has caused over 7 million deaths worldwide since its onset in 2019, and the virus remains a significant health threat. Identifying sensitive and specific biomarkers, along with elucidating immune-mediated mechanisms, is essential for
Yumei Zhou, Pengbei Fan, Haiyun Zhang, Haiyun Zhang, Shuai Han, Minghua Bai, Ji Wang, Qi Wang, Qi Wang   +8 more
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Association study of diabetes mellitus and body constitution of traditional Chinese medicine

Traditional Medicine and Modern Medicine, 2019
Objective: We report on the association between traditional Chinese medicine (TCM) constitution and diabetes mellitus (DM) and provide epidemiological evidence for the theory of correlation between constitution and disease.Methods: A total of 3748 participants were used for data analysis, and all study subjects underwent a complete clinical baseline ...
Nabijan Mohammadturusn, Yizhe Xu, Fei Xu, Yuanhao Zhang, Zihui Tang, Wenxian Liu   +5 more
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