Results 31 to 40 of about 61,486 (255)

Assessing the associations of 1,400 blood metabolites with major depressive disorder: a Mendelian randomization study

Frontiers in Psychiatry
Background and objectivesMajor Depressive Disorder (MDD) is one of the most prevalent and debilitating health conditions worldwide. Previous studies have reported a link between metabolic dysregulation and MDD. However, evidence for a causal relationship
Tiantian Dong, Tiantian Dong, Xingxin Wang, Zhixia Jia, Jiguo Yang, Yuanxiang Liu   +5 more
doaj   +1 more source

Integrated nursing of Traditional Chinese and western medicine for a patient undergoing thrombolytic therapy for acute mesenteric venous thrombosis (1例急性肠系膜静脉血栓患者溶栓后的中西医结合护理)

中西医结合护理, 2021
This paper summarized the nursing of integrated Traditional Chinese and western medicine for a patient undergoing thrombolytic therapy for acute mesenteric venous thrombosis.
TONG Fenfei (仝粉飞), ZHEN Wen (郑雯), ZHI Hui (智慧), LOU Jinjing (刘津京)   +3 more
doaj   +3 more sources

Guidelines of Integrated Traditional Chinese and Western Medicine for Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (2025 Edition) [PDF]

Zhongguo quanke yixue
Chronic obstructive pulmonary disease(COPD) poses a serious threat to human health, making it one of the major global public health burdens. In 2023, an expert consensus group was established to address key clinical questions in the integrated Chinese ...
Guideline Working Group of Integrated Traditional Chinese and Western Medicine Management for Chronic Obstructive Pulmonary Disease
doaj   +1 more source

Identification of sex-specific biomarkers related to programmed cell death and analysis of immune cells in ankylosing spondylitis

Scientific Reports
Ankylosing spondylitis (AS) stands as a persistent inflammatory ailment predominantly impacting the axial skeleton, with the immune system and inflammation intricately entwined in its pathogenesis.
Tiantian Dong, Xuhao Li, Wenyan Yu, Yuanxiang Liu, Jiguo Yang   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Targeting digestive system cancers with isoliquiritigenin: a comprehensive review of antitumor mechanisms

Frontiers in Pharmacology
Digestive system malignancies, including gastric, colorectal, and liver cancers, account for a substantial proportion of global cancer morbidity and mortality.
Zhichun Li, Ruohan Feng, Jinze Li, Jinglu Bai, Nuo Li, Zhenhua Cui, Zhenhua Cui, Xiaobin Zhang   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Guidelines for the diagnosis and treatment of knee osteoarthritis with integrative medicine based on traditional Chinese medicine

Frontiers in Medicine, 2023
Knee osteoarthritis (KOA) is a common geriatric disease in middle-aged and elderly people. Its main pathological characteristics are articular cartilage degeneration, changes in subchondral bone reactivity, osteophyte formation at joint edges, synovial ...
Lingfeng Zeng, Lingfeng Zeng, Lingfeng Zeng, Guanghui Zhou, Weiyi Yang, Jun Liu, Jun Liu   +6 more
doaj   +1 more source

External application of traditional Chinese medicine in the treatment of bone cancer pain: a meta-analysis [PDF]

Supportive Care in Cancer, 2015
Bone cancer pain presents a clinical challenge with limitations of current treatments. Many patients seek additional therapies that may relieve pain. Many external applications of traditional Chinese medicines (EAs-TCMs) have been evaluated in clinical trials, but fewer are known about them outside of China. The objective of this study is to assess the
Xiangyong, Yan, Zhongsheng, Yan, Wenchao, Liu, Hui, Ding, Shuzhou, Qiao, Gang, Chen, XiaoHui, Wang, Lian, Zhang   +7 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source