Results 121 to 130 of about 3,233 (205)

The Effect of Prophylactic Protection of Inferior Parathyroid Gland Vein Blood Supply on Reducing Postoperative Hypoparathyroidism

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background The objective of this study was to verify that a strategy involving prophylactic exposure of the inferior parathyroid glands and preservation of their venous blood flow—achieved through early identification and protection of their venous drainage—can enhance the success rate of maintaining glandular perfusion and effectively reduce ...
Liping Liu   +5 more
wiley   +1 more source

AI‐Assisted Early Clinical Diagnosis of External Auditory Canal Squamous Cell Carcinoma: A Rare Case in a Young Male From Pakistan

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 36‐year‐old with refractory otorrhea, otalgia, and facial palsy had HRCT bony erosion. Microsoft Copilot flagged malignancy; biopsy confirmed T1N0M0 squamous cell carcinoma. Curative resection achieved clear margins. Cranial nerve involvement demands biopsy regardless of age; AI aids but cannot replace clinical judgment.
Mah Gul Summan   +7 more
wiley   +1 more source

Hyperglycemia‐Induced Microglial CTSS Disrupts Blood‐Retinal Barrier Integrity via PAR2‐Dependent Downregulation of Endothelial MFSD2A

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Hyperglycemia induces retinal microglial activation and CTSS upregulation, disrupting microglia‐endothelial crosstalk via PAR2‐dependent MFSD2A suppression. Abnormal activation of microglia amplifies retinal inflammatory cascade, enhances transcytosis, compromises BRB integrity, and accelerates DR progression.
Chengye Xu   +8 more
wiley   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen   +8 more
wiley   +1 more source

A Topical Chinese Herbal Alleviates Psoriasis by Regulating Keratinocytes Pyroptosis Through Inhibition of NLRP3 Inflammasome Activation

open access: yesClinical, Cosmetic and Investigational Dermatology
Xuewan Wang,1 Yutong Deng,1 Xuewen Ren,2 Yatong Li,1 Tangyunni Liu,1 Bo Hu,1 Yuanwen Li1 1Department of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Department of Dermatology, Shanxi ...
Wang X   +6 more
doaj  

Acrodermatitis Dysmetabolica as a Cutaneous Manifestation of Isoleucine Deficiency in Maple Syrup Urine Disease: A Systematic Review of Reported Cases

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aim Maple Syrup Urine Disease (MSUD) is a metabolic disorder affecting branched‐chain amino acid metabolism. While neurological symptoms are well‐characterized, cutaneous manifestations such as acrodermatitis dysmetabolica (AD) caused by isoleucine deficiency remain underrecognized.
Bahareh Abtahi‐naeini   +4 more
wiley   +1 more source

Nanostructured lipid carriers and natural deep eutectic solvents: a highly advantageous combination for the encapsulation of curcumin

open access: yesJournal of Chemical Technology &Biotechnology, Volume 101, Issue 10, Page 1980-1999, October 2026.
Abstract BACKGROUND Curcumin is a naturally derived polyphenol known for its potent biological properties. Its therapeutic potential, however, is hindered by low bioavailability. Nanostructured lipid carriers (NLCs) have emerged as advanced delivery systems to overcome such limitations. Natural deep eutectic solvents (NADESs) have garnered attention as
Kyriaki Safari   +5 more
wiley   +1 more source

Effect of Golden Wanhong Ointment on wound microbiota in patients with diabetic foot ulcer. [PDF]

open access: yesFront Cell Infect Microbiol
Qiu R, Yang L, Li X, Li S, Liu L, Che J.
europepmc   +1 more source

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang   +9 more
wiley   +1 more source

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