Results 301 to 310 of about 143,679 (362)

Optimization of Immunotherapy Strategies Based on Spatiotemporal Heterogeneity of Tumour‐Associated Tissue‐Resident Memory T Cells

Immunology, Volume 175, Issue 2, Page 123-133, June 2025.
The tumour microenvironment (TME) and tumour evolution stage lead to temporal and spatial heterogeneity in tumour‐resident macrophages (TRMs), affecting their phenotype and function across different stages and tumour types. While TRMs infiltration is often linked to positive immunotherapy responses and prognosis, some subtypes may negatively impact ...
Yile Shang, Yinjun He, Xiang Zhang, Wenguang He, Hanju Hua, Feng Ye, Xile Zhou, Yandong Li, Weixiang Zhong, Guosheng Wu, Weiqin Jiang   +10 more
wiley   +1 more source

Screening of 60,544 Traditional Chinese Medicine (TCM) compounds against the most oncogenic K-Ras(G12D) mutation switch-I/II allosteric pocket: a comprehensive structure-based screening and pharmacokinetics evaluation

Ibrahim Oluwatobi Kehinde, Archimede Rotondo, Giuseppe Pellicane, Mahmoud A. A. Ibrahim, Mahmoud E. S. Soliman   +4 more
openalex   +1 more source

Cultural Influences, Experiences and Interventions Targeting Self‐Management Behaviours for Prediabetes or Type 2 Diabetes in First‐Generation Immigrants: A Scoping Review

Journal of Advanced Nursing, Volume 81, Issue 6, Page 2929-2945, June 2025.
ABSTRACT Aim To map the existing evidence and identify research gaps regarding the self‐management of prediabetes or type 2 diabetes among first‐generation immigrants ≥ 18 years. Design A scoping review followed the JBI guidelines and was in accordance with the PRISMA extension for Scoping Reviews.
Min Zhang, Kirsten Coppell, Johnny Lo, Lisa Whitehead   +3 more
wiley   +1 more source

Research on the Advantages, Shortcomings, and Countermeasures of Contemporary Traditional Chinese Medicine Talent Cultivation Models based on the Growth Paths of Renowned TCM Practitioners

Huimin Yan, Zhaofu Li, Su-Ling Zeng, Niiqin Xiao, Jing Xie, Bingbing Chen, Bo Yang, Zhaohu Xie   +7 more
openalex   +1 more source

Cordycepin ameliorates diabetic nephropathy injury by activating the SLC7A11/GPX4 pathway

Journal of Diabetes Investigation, Volume 16, Issue 6, Page 992-1000, June 2025.
Cordycepin suppressed HG‐induced apoptosis, inflammation, and ferroptosis in podocytes in vitro, and ameliorated diabetic‐induced renal injury in mouse models by activating the SLC7A11/GPX4 pathway, indicating a viable therapeutic strategy for DN patients.
Bing Wu, Jing Wang, Xiaohui Yan, Gang Jin, Qiong Wang   +4 more
wiley   +1 more source

Chinese Expert Consensus on Integrated Chinese and Western Medicine for the Treatment of Tic Disorders

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Objective Tic disorders are neurodevelopmental conditions that manifest in childhood or adolescence and can significantly impact the quality of life of affected children and their families to varying degrees. Integrated traditional Chinese and Western medicine treatment strategies have demonstrated more pronounced efficacy and better safety ...
Rong Ma, Sumei Wang, Yi Zheng, Jian Chen, Wenxiong Chen, Xia Cui, Yonghua Cui, Yanzhao Guo, Fei Han, Xinmin Han, Daohan Wang, Fan He, Ping Rong, Yan Hu, Yi Huang, Xiaoyan Ke, Bo Li, Min Li, Ruiben Li, Huanzhong Liu, Jing Liu, Zhisheng Liu, Xuerong Luo, Bingxiang Ma, Ping Shi, Jiaxin Sun, Hua Wang, Liping Wu, Min Wu, Haihong Yan, Baoqing Zhang, Jinsong Zhang, Junhua Zhang, Xilian Zhang, Xin Zhang, the Standard Research Project Group on Prevention and Treatment Strategies of Integrated Chinese and Western Medicine   +35 more
wiley   +1 more source

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu, Wei Liu, Jianxin Wang, Wei Chen, Mengyao Shi, Lu Zhang, Hui Wang, Huanzhang Ding, Xiao Ma, Yating Gao, Zengtao Sun, Jiangtao Lin, Hongchun Zhang, Suyun Li, Zhuying Li, Zhenhui Lu, Fuqiang Wen, Zegeng Li   +17 more
wiley   +1 more source

Large Language Models in Integrative Medicine: Progress, Challenges, and Opportunities

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Integrating Traditional Chinese Medicine (TCM) and Modern Medicine faces significant barriers, including the absence of unified frameworks and standardized diagnostic criteria. While Large Language Models (LLMs) in Medicine hold transformative potential to bridge these gaps, their application in integrative medicine remains underexplored and ...
Hiu Fung Yip, Zeming Li, Lu Zhang, Aiping Lyu   +3 more
wiley   +1 more source

IDEAL‐Acu: A Methodological Framework for Evaluating the Effects of Acupuncture

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Objectives The demand for high‐quality clinical evidence supporting acupuncture remains urgent, necessitating the establishment of a suitable methodological framework to promote its generation. Methods Following internal deliberations and extensive online discussions with experts in the IDEAL Collaboration, we proposed the IDEAL‐Acu framework ...
Jiali Liu, Xiaochao Luo, Yemeng Chen, Ling Zhao, Minghong Yao, Jiajie Yu, Jiahui Yang, Ling Li, Xin Sun   +8 more
wiley   +1 more source

Guidelines on Treating Fibromyalgia With Nonpharmacological Therapies in China

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Fibromyalgia is a prevalent chronic condition marked by widespread pain, fatigue, and other debilitating symptoms. This guideline provides evidence‐based recommendations for nonpharmacological treatments, developed by a multidisciplinary expert group, including specialists in rheumatology, rehabilitation, pain management, traditional Chinese ...
Xuanlin Li, Hejing Pan, Liaoyao Wang, Qi Zhou, Yanfang Ma, Qi Wang, Mingzhu Wang, Zhijun Xie, Haichang Li, Lu Chen, Lin Huang, Yaolong Chen, Chengping Wen   +12 more
wiley   +1 more source