Results 91 to 100 of about 9,836,213 (398)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Blood metabolites and chronic kidney disease: a Mendelian randomization study

BMC Medical Genomics
Background Human blood metabolites have demonstrated close associations with chronic kidney disease (CKD) in observational studies. Nonetheless, the causal relationship between metabolites and CKD is still unclear.
Yawei Hou, Zhenwei Xiao, Yushuo Zhu, Yameng Li, Qinglin Liu, Zhenguo Wang   +5 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

FengShui – a systematic research of vernacular sustainable development In Ancient China and its lessons for future [PDF]

, 2007
Creating and keeping balance is the basic and the most important principle of Chinese traditional philosophy. It provides the fundamental philosophical basis for Chinese FengShui in pursuing coexistence between human and nature.
Ceranic, Boris, Zhong, Z.
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Historical Geographical Information System (HGIS): social trajectories of two Chinese historical figures Su Shi and Zuo Zongtang in spatial context

Heritage Science
Historical figures have important significance worldwide. This paper introduces the concept of historical Geographical Information System (HGIS) using the lives of two personalities from Chinese history as case studies: Su Shi, a literary figure of the ...
Jing Fu, Kangsheng Chen, Jianxin Qin, Liguo Yang, Peilin Liu, Wenwu Zheng   +5 more
doaj   +1 more source

Efficacy and safety of Danhong injection on inflammatory factors and vascular endothelial function in patients with unstable angina pectoris: a systematic review and meta-analysis of randomized clinical trials

Frontiers in Pharmacology
BackgroundInflammatory factors and vascular endothelial damage are significantly involved in the development of unstable angina pectoris (UAP). Danhong injection (DHI) is a compound injection composed of Salvia miltiorrhiza and Carthamus tinctorius ...
Zunqi Kan, Wenli Yan, Cong Chen, Huanyu Gao, Yongmei Song   +4 more
doaj   +1 more source

Traditional Culture: “Small” Wooden Temples of the Russian North

Проект Байкал, 2021
Wooden chapels are a bright and typical phenomenon of the traditional culture. The chapels were non-altar temples of a small peasant parish, which retained their independence, providing a special atmosphere for performing rituals.
Anna Permilovskaya
doaj  

Mathematics Learning Within Culture And Nation Character: Using Traditional Dance In Learning The Concept Of Symmetry At Grade IV Primary School [PDF]

, 2011
This paper introduces a new approach in mathematics learning within culture and nation character. Indonesian traditional dances are used as a context in learning the concept of symmetry.
Yullys , Helsa, Yusuf , Hartono
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source