Results 101 to 110 of about 511,206 (310)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Do psychiatric patients benefit from non-medical help?

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: The aim of this study is to investigate the modern medical and traditional help seeking among psychiatric patients, and to determine the related factors to their preferences.
Elif Mutlu   +2 more
doaj  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Cantharanthus Roseus Leaf Extract Accelerates Healing Of Wound Wistar Rat [PDF]

open access: yes, 2013
Cantharantus roseus (C. roseus) is a medical plant that has been used to treat various diseases. This study was carried to determine C. roseus leaf extract able to acclerate wound healing in Wistar rat. Full skin-tickness round wounds were created on the
Anom-Dada, I. K. (I)   +3 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Western health practitioners’ view about African traditional health practitioners’ treatment and care of people living with HIV/AIDS

open access: yesCurationis, 2006
African traditional health practitioners are an important source of health care for many South Africans. Thus, they are a health resource in this society.
JV Summerton
doaj   +1 more source

Relationships and implications for complementary and alternative medicine in Aotearoa New Zealand: A discussion paper [PDF]

open access: yes, 2019
The purpose of this paper is to initiate a discussion on contextualising the relationship between the nursing profession and complementary and alternative medicine (CAM) within Aotearoa New Zealand.
Te Huia, Maria
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Simbiosis Pengetahuan: Menelusuri Kombinasi Penyembuhan Islami dan Tradisional dalam Naskah Mujarrabat Jawan

open access: yesSuluk: Jurnal Bahasa, Sastra, dan Budaya
There were various manuscripts spread in the archipelago. Some of the manuscripts are the source of history, literature, and religious principle, and some of them are source of medical healing as ancestral heritage.
Lutfiyah Alindah
doaj   +1 more source

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