Results 231 to 240 of about 5,528,017 (309)

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

Advanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu, Zhiyu Tian, Zhengxian Zhang, Xinbei Li   +3 more
wiley   +1 more source

Syndirella: synthesis-directed fragment elaboration enables extensive and cost-effective binding site exploration beyond catalog compounds. [PDF]

Chem Sci
Fieseler KK, Winokan M, Morrone JA, Deane CM, von Delft F, Thompson W.   +5 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Allergic rhinitis as a potentially modifiable contributor to small airway dysfunction and incomplete clinical remission in severe asthma. [PDF]

World Allergy Organ J
Wu H, Ouyang Q.
europepmc   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Climate resilience mechanisms of vernacular dwellings in China's Yangtze River delta region: a study based on a multi-level analytical framework. [PDF]

Sci Rep
Min T, Zhang T.
europepmc   +1 more source

Efficient Cholesteric Liquid Crystal Waveguide Polarizing Splitters for High‐Sensitivity Chip‐Scale Atomic Magnetometry

Advanced Science, EarlyView.
An integrated polarimetry architecture based on a cholesteric liquid crystal waveguide polarization splitter overcomes the volumetric bottleneck in chip‐scale atomic magnetometers. By leveraging Bragg‐selective reflection and total‐internal‐reflection‐induced helicity inversion, this ultrathin device enables efficient circular polarization splitting ...
Zhibo Cui, Chuang Wang, Xiangyang Zhou, Gaopu Hou, Jinsheng Hu, Mao Ye, Xu Xiao, Zhen Chai, Yishi Weng, Yuning Zhang   +9 more
wiley   +1 more source

Physics-Informed Graph Diffusion Model for Cross-Scale Performance Prediction of Silver Nanowire Percolation Networks. [PDF]

ACS Omega
Xiong W, He X, Huang Z, Wang H, Zeng X, Liu X, Lyu L, Hu B.   +7 more
europepmc   +1 more source