Results 121 to 130 of about 7,407,823 (255)

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao   +7 more
wiley   +1 more source

Education and public housing

open access: yes, 2005
Government housing assistance is provided to achieve various outcomes, including greater affordability. The shelter outcomes of assistance packages have been well documented by Australian policy makers and researchers. However, beyond the shelter impacts,
Hafekost, Ian P.   +4 more
core  

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

Analysis of impediments to fair housing choice, 1997 Impediments to fair housing choice Fair housing action plan, 1997-2000

open access: yes, 1997
Table of Contents -- Introduction -- What is Fair Housing? -- What is Prohibited? -- What is Not Covered by the Fair Housing Act? -- Summary of Fair Housing and Related Laws -- Population and Demographic Trends -- Impediments to Fair Housing Choice ...
Kansas Division of Housing
core  

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

Integrated study on the deterioration investigation and intervention treatment of rural vacant traditional dwellings under population contraction

open access: yesJournal of Asian Architecture and Building Engineering
The rapid advancement of urbanization in China has exacerbated the contraction of many rural populations and as a result, the abandonment of many traditional dwellings.
Tingshen Li, Xuehong Tan, Pin Liu
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Housing Programs for Low-Income Households [PDF]

open access: yes
The primary purposes of this paper are to (1) consider the justifications that have been offered for housing subsidies to low-income households and the implications of these justifications for the evaluation and design of housing programs, (2) describe ...
Edgar O. Olsen
core  

Charting Endocrine Progenitors Across Species and Organs

open access: yesAdvanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing   +21 more
wiley   +1 more source

Housing resources [1997]

open access: yes, 1997
Homeownership -- Rental Housing -- Housing with Supportive Services -- Asset Management -- Information ...
Kansas Division of Housing
core  

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