Results 41 to 50 of about 1,408,559 (290)

The impact of UTeach observation protocol-based multiple-source feedback on improving the quality of online teaching in medical education

BMC Medical Education
Background The ability to teach, as a core competency, has always suffered from a lack of systematic cultivation. Objective This study aimed to explore the difference in teaching quality before and after the application of the UTOP (UTeach observation ...
Tongyan Zhang, Yan Li, Qian Du, Yanyan Ren, Wei Mu, Yujie Duan, Xin Yang, Hailong Ran, Jiao Li   +8 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Both Sides of the Story: Communication Ethics in Mediatized Worlds [PDF]

, 2016
Current transformations in the media landscape are challenging contemporary communication and media ethics in at least 2 ways. First, digitization of the media creates new ethical problems that stimulate calls for a redefinition of the norms and values ...
Eberwein, T., Porlezza, C.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

ALMUSTRA: An Augmented reality application for introducing traditional musical instruments

Jurnal Kependidikan: Penelitian Inovasi Pembelajaran
Traditional Indonesian musical instruments reflect the richness and diversity of culture and are an integral part of people's lives. However, in recent decades, it has faced challenges in preserving and introducing it to the younger generation.
Evangs Mailoa, Elvira Resti Widyasari
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

SME bonds in European countries as a new approach to financing [PDF]

, 2018
Nowadays a lot of new financial instruments for SMEs innovation projects are getting more popular in the business environment. A great number of them are traditional like credit loans at the same time we can observe the appearance of innovative ones ...
Britchenko, Igor, Dyba, M., Polishchuk, Yevheniia, Svyrydenko, O.   +3 more
core  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Systematization of Instruments of Social and Economic Responsibility of Enterprises: Theoretical Aspect [PDF]

Problemi Ekonomiki, 2016
The aim of the article is systematization of instruments for implementation of social and economic responsibility of enterprises in Ukraine and theoretical consideration of the presented instruments.
Dielini Maryna M.
doaj