Results 181 to 190 of about 873,302 (263)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Are we romanticizing traditional knowledge? A plea for more experimental studies in ethnobiology. [PDF]

J Ethnobiol Ethnomed
Leonti M.
europepmc   +1 more source

Engineering Layered Magnetic Hydrogels for Cell Placement via Shear and Magnetic Field‐Induced Assembly

Advanced Materials, EarlyView.
Magnetic particles are organized into layered architectures by combining shear flow and magnetic fields, with the resulting structures governed by appropriate Mason numbers. The programmed assemblies provide spatial guidance for cell placement, linking field‐controlled self‐assembly, flow‐induced structuring and biological organization.
Guillermo Camacho, Jose R. Morillas, Jesús García‐Gutiérrez, Stefania Nardecchia, Óscar Martínez‐Cano, Juan de Vicente   +5 more
wiley   +1 more source

Local and traditional knowledge systems, resistance, and socioenvironmental justice. [PDF]

J Ethnobiol Ethnomed
Hanazaki N.
europepmc   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Tracing gender variation in traditional knowledge: participatory tools to promote conservation in a Quilombola community in Brazil. [PDF]

J Ethnobiol Ethnomed
Cantelli D, Gonçalves MC, da Silva VO, da Silva DN, Hanazaki N.   +4 more
europepmc   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Farmers' traditional knowledge on seasonal frost management and their tree preferences in frost affected highlands of Amhara region, Ethiopia. [PDF]

Heliyon
Mengesha YA, Wolle HS, Ayana DA, Belayneh AH, Yewogu SW, Gebremedhin SE, Worku AE, Desta AY, Yesufe AT.   +8 more
europepmc   +1 more source

Giant Anisotropy and High Second‐Order Nonlinearity of 3R‐MoS2 for Multifunctional Photonics

Advanced Materials, EarlyView.
Graphical abstract highlights, 3R‐polytype of MoS2 (3R‐MoS2) as a multifunctional photonic platform enabled by giant optical anisotropy and optical nonlinearities, demonstrating subdiffractional waveguiding, giant second‐harmonic (SH) generation, and high‐performance reflective polarization control.
Georgy Ermolaev, Dmitriy Grudinin, Liudmila Klimova, Adilet Toksumakov, Mikhail Gubin, Anton Minnekhanov, Aleksandr Slavich, Mikhail Mironov, Arslan Mazitov, Dmitry Yakubovsky, Nikolay Pak, Andrey Vyshnevyy, Ivan Kruglov, Gleb Tselikov, Alexei Prokhorov, Aleksey Arsenin, Kostya S. Novoselov, Valentyn Volkov   +17 more
wiley   +1 more source

Traditional knowledge of wild plants on traditional tools, materials, products and economic practices in southern Yemen. [PDF]

J Ethnobiol Ethnomed
Al-Fatimi M.
europepmc   +1 more source