This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source
Euphorbia-derived natural products with potential for use in health maintenance [PDF]
Euphorbia genus (Euphorbiaceae family), which is the third largest genus of angiosperm plants comprising ca. 2000 recognized species, is used all over the world in traditional medicine, especially in the traditional Chinese medicine. Members of this taxa
Adedoyin+34 more
core +4 more sources
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
in Traditional Persian Medicine
Traditional Persian medicine is based on humoral medical concepts. In the case of abundant blood in the body, tabi’at (body nature) deals with this imbalance by elimination of the morbid substances via some controlling mechanisms.
Majid Nimrouzi PhDc+4 more
doaj +1 more source
The Forensic Characterization of Bacterial and Fungal Organisms in Traditional Chinese Medicine [PDF]
There has been an increase in use of Traditional Chinese Medicine (TCM) in the United States because they are less expensive and believed to be more effective with less adverse effects in comparison to traditional pharmaceutics.
Ehrhardt, Christopher J+3 more
core +1 more source
Response to “Radiation Therapeutic Gain and Asian Botanicals,” by Stephen Sagar [PDF]
Numerous botanical agents, many of which are used in whole medical system practices (i.e. traditional Chinese medicine, Ayurvedic medicine, etc.), have been shown to exhibit radiomodifying effects on tumors and normal tissues in-vitro and invivo studies.
Lawenda, Brian D.
core +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Cancer Niche as a Garbage Disposal Machine: Implications of TCM-Mediated Balance of Body-Disease for Treatment of Cancer. [PDF]
Cancer epidemic led to worldwide to search for a new "game changer" concept to govern cancer research and cancer treatment. Western medicine-based cancer research has been extending the impasse without resolution in sigh for improving survival of ...
Lee, Katherine L+2 more
core
Cherokee relationships to land: Reflections on a historic plant gathering agreement between Buffalo National River and the Cherokee Nation [PDF]
This piece reflects on my involvement in a historic agreement between Buffalo National River and the Cherokee Nation regarding the implementation of the “Gathering of Certain Plants or Plant Parts by Federally Recognized Indian Tribes for Traditional ...
Carroll, Clint
core
Traditional vocations and modern professions among Tamil Brahmans in colonial and post-colonial south India [PDF]
Since the nineteenth century, Tamil Brahmans have been very well represented in the educated professions, especially law and administration, medicine, engineering and nowadays, information technology.
Fuller, C. J., Narasimhan, Haripriya
core +1 more source