Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The present pot experiment studied the effect of different soil moisture contents (60 - 70% CWC (capillary water capacity) - control; 30 - 35% CWC - water stress) on buckwheat productivity, the gas exchange parameters and health of buckwheat nuts. It was
Agnieszka Pszczółkowska +5 more
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
The design and results of the study of the comb-forming fertilizer [PDF]
The article presents the results of research into the physical and mechanical properties of soils and fertilizers, the effectiveness of the method of applying mineral fertilizers layer by layer on the formed dams, the development of the design of ...
Abdurakhmonovich Razzakov Bakhodirjon +4 more
doaj +1 more source
The role and future of traditional leaders in South Africa [PDF]
Traditional authorities play an important role in South Africa. Not everyone is, however, prepared to recognise them as role players. In government circles, on the one hand, a tendency exists to marginalise the role of traditional leaders and, on the ...
Traditional Authorities Research Group +1 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Field Notes: News from Traditional Arts Indiana [PDF]
This issue features: In this issue: Arts Fair on the Square, Volbrecht Luthier Exhibit, Bernice Enyeart Quilt Exhibit, Indiana Festival, Marion Octoberfest, TAI at the Indiana State Fair, Rotating Exhibit Network, and David and Joel Straubinger, flute ...
Traditional Arts Indiana
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
A method for comparing traditional and component-based models in information systems re-engineering [PDF]
Many organisations have become aware of the limitations of their legacy systems to adapt to new technical requirements. Trends towards e-commerce applications, platform independence, reusability of pre-built components, capacity for reconfiguration and ...
Mark Toleman +5 more
core +1 more source

