Results 61 to 70 of about 4,432,034 (303)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

LET’S “HAVE A LISTEN” TO A RADIO TALK [PDF]

open access: yes, 2015
This paper deals with a traditional program in the radio broadcast in Semarang. It analyzes a short piece of radio talks, which contains Javanese knowledge performed by the radio announcers in Indonesian. The traditional values, used to be reflected in
Purwoko , Herudjati
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Values based practice and authoritarianism [PDF]

open access: yes, 2014
Values based practice (VBP) is a radical view of the place of values in medicine which develops from a philosophical analysis of values, illness and the role of ethical principles. It denies two attractive and traditional but misguided views of medicine:
Thornton, Tim
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Evolution in Style of Shanghai Women in the 1920s and 1930s

open access: yesRUDN Journal of World History, 2012
The article deals with the transformation of the appearance of women in Shanghai as a process. Manchu women typically wore a one-piece dress that retrospectively came to be known as the qípáo.
Yu Andreevna Seliverstovа
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

SPIRITUAL DETERMINANTS OF SUSTAINABLE DEVELOPMENT

open access: yesЮг России: экология, развитие, 2017
Aim. The aim of the research is to study the specific determinants, motivational factors, tools and approaches that make up the mechanism for the implementation of sustainable development (the region of Southern Russia).Material and methods.
M. I. Bilalov
doaj   +1 more source

Children\u27s Books as Cultural Products: A Qualitative Study of Cultural Representation in Hmong and Non-Hmong American Books [PDF]

open access: yes, 2019
This study examined the type of cultural practices and values depicted within Hmong American children’s books in comparison to non-Hmong American children’s books from the United States. The purpose was to explore if prior Hmong traditional practices and
Her, Malina
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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