Results 31 to 40 of about 24,139,640 (291)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

EFFECT OF DIFFERENT PLANTING SYSTEM ON SOIL, WATER AND RICE PRODUCTIVITY IN THE NORTHERN PART OF DELTA IN EGYPT [PDF]

open access: yesJournal of Soil Sciences and Agricultural Engineering, 2013
Water scarcity and soil salinity are the main constrains for rice production in Egypt. Rice is the greatest consumer of water among all crops. A system of growing rice on raised beds or levees and system of rice intensification (intermittent irrigation ...
A. K. Salem   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Assessment of Traditional Groundwater Governance Features UsingEffective Groundwater Governance [PDF]

open access: yesDānishhā-yi būmī-i Īrān, 2019
In arid and semi-arid areas, water shortage leads people to the creation of traditional water management appropriate to local characteristics. Iran is one of the oldest civilizations of the world that has a unique water supply system according to social,
Mohammad Ebrahim Banihabib   +1 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

San Antonio Water System: Title XVI feasibility report, brackish groundwater desalination program for the Bureau of Reclamation

open access: yes, 2022
San Antonio Water System Title XVI Feasibility Report Brackish Groundwater Desalination Program for the Bureau of Reclamation May 2011 Brackish Groundwater Desalination Program Title XVI Feasibility Report May 2011 Page ii Table of Contents 1.0 ...
San Antonio Water System (Tex.); United States. Bureau of Reclamation;
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

A drug dispensing system for water quality detection based on spectrophotometry

open access: yesMeasurement + Control
Since the advent of industrialization, environmental pollution has become increasingly severe. Ensuring the ecological safety of water bodies and human health has made water quality testing an important means.
Zhuoshi Zhang, Yun Qian, Pan Li, Man Gao
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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