Results 111 to 120 of about 41,264 (308)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Pervasive Uncertainty in Second Modernity: an Empirical Test [PDF]

open access: yes
Recent discussion of social change implies that, for a number of reasons, to do with globalisation, shifts in family life styles and labour markets, more critical attitudes toward the authority of officials and experts and greater awareness of ...
Peter Taylor-Gooby
core  

ОБРІЇ НОВОЇ МЕТАФІЗИКИ У ФІЛОСОФІЇ ПОСТТРАДИЦІОНАЛІЗМУ. (Horizons of the New Metaphysics In Post-Traditionalist Philosophy.) [PDF]

open access: yes, 2013
У статті розглядаються витоки "Нової Метафізики" як критичної рецепції холістської онтології інтегрального традиціоналізму Рене Генона. Простежуються витоки та логічні підстави становлення новітньої посттрадиціоналістської думки та її співвідношення з ...
Вишинський, С. (S. Vyshynskyi)
core  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

From the Conception of Man to the Critique of Collectivism: The Structure of Alija Izetbegović’s Socio-Political Thought

open access: yesDruštvene i Humanističke Studije
The socio-political thought of Alija Izetbegović occupies a distinctive place within contemporary Islamic philosophy, where it bridges theological anthropology and the political theory of modernity.
Asim Delibašić
doaj   +1 more source

INSTITUTIONS AND VALUES OF ROMANIANS – COMPARATIVE ANALYSIS OF HISTORICAL REGIONS [PDF]

open access: yes
Starting from the results of a national survey, a questionnaire on the values of Romanians was applied in April 2008 which was used for a comparative analysis of historical regions of Romania: Moldova, Bucharest, Dobrogea, Transilvania and Muntenia ...
Asandului Laura   +2 more
core  

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