Results 91 to 100 of about 2,245,066 (346)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
CONTEMPORARY CONFUCIAN AND ISLAMIC APPROACHES TO DEMOCRACY AND HUMAN RIGHTS [PDF]
, 2012 Both Confucian and Islamic traditions stand in fraught and internally contested relationships with democracy and human rights. It can easily appear that the two traditions are in analogous positions with respect to the values associated with modernity ...
Angle, Stephen
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Tradition ... Tradition ... [PDF]
Journal of the Pediatric Infectious Diseases Society, 2014 Ilan, Youngster, Ben Z, Katz
openaire +2 more sources
A Modern Natural Theology? [PDF]
, 2012 The author examines two different traditions of nineteenth-century natural theology and their reappearance in a modern work. Michael Denton\'s Nature\'s Destiny is used as an example of modern natural theology, showing how current writers attempt to ...
Stanley, Matthew
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
TRADITIONAL RELIGIONS UNDER GLOBALIZATION: SOCIAL FUNCTIONS OF PRESERVING IDENTITY AND TRADITIONS
Вестник Северо-Кавказского федерального университета, 2022 The article provides a view on various approaches to traditional religions given the new trends in the social development. One of the major issues related to the influence of religion on the modern society is determining the true role of the religious in
Ivan Inanovich Belashov
doaj
Meteoritics and cosmology among the Aboriginal cultures of Central Australia
, 2011 The night sky played an important role in the social structure, oral traditions, and cosmology of the Arrernte and Luritja Aboriginal cultures of Central Australia. A component of this cosmology relates to meteors, meteorites, and impact craters.
Hamacher, Duane W.
core
Nationhood and Constitutionalism in the Dutch Republic: An Examination of Grotius' Antiquity of the Batavian Republic [PDF]
, 2017 The emphasis in contemporary democratic theory and in the history of political thought on the ‘natural rights’ theory of popular sovereignty of Locke, precursors of which are found in the work of Hugo Grotius and others, obscures
Alexander-Davey, Ethan
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source