Results 41 to 50 of about 499,190 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Acta Universitatis Lodziensis. Folia Litteraria Polonica, 2019 The aim of the article was to describe the collection of manuscripts preserved in the family archives as a memorial to Sabina Grzegorzewska née Gostkowska, a 19th‑century writer, which are currently in the possession of The Scientific Library of the PAAS
Maria Berkan-Jabłońska
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Secularization and Postmodernism: Religious Processes among the Young in Today’s Russia and Europe and Their Social and Theological Reflection [PDF]
Вестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2014 The article is devoted to the burning issue of religiosity among contemporary Russian youths. Methodologically, the research is based on a comparative analysis of the religious processes among young people in Russia and Germany during the last ten years.
Georgij Orekhanov
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
RUSSIAN NAMING TRADITIONS [PDF]
, 2015 The article dwells on Russian naming traditions. It is shown how language and culture interact, how culture impacts naming traditions.
M.A. Belykh
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Conversation about local customs and traditions
, 2019 Neeraj and Rajdeep discuss their customs and traditions, debating whether some of them should be preserved or discarded.
Martinez, Philippe Antoine
core +1 more source