Traffic forecasts under uncertainty and capacity constraints [PDF]
Traffic forecasts provide essential input for the appraisal of transport investment projects. However, according to recent empirical evidence, long-term predictions are subject to high levels of uncertainty.
Anna Matas +2 more
core
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source
Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo +9 more
wiley +1 more source
A Noninvasive Approach to Study Localized Forces in 3D Epithelia
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand +9 more
wiley +1 more source
Mutual Adaptation and Influence: Review of Latent Dynamics Models in Human–Robot Interaction
Robots are becoming better teammates by learning hidden patterns in how people act. This review covers how state‐of‐the‐art approaches leverage these patterns to help robots not only react but also anticipate and guide cooperation. Here, we synthesize a unifying framework for these approaches, classify and review existing works, and highlight key ...
Mason O. Smith +4 more
wiley +1 more source
Autonomous Navigation of Pollen‐Inspired Magnetic Microrobots for Biomedical Applications
A sunflower pollen‐inspired magnetic microrobot enables controlled rolling navigation in vessel‐like environments. Its open geometry reduces hydrodynamic drag, while vision‐based closed‐loop control, shortest‐path planning, and reinforcement learning support target‐reaching and maze navigation with microrobot‐scale accuracy, highlighting a route toward
Ali Anil Demircali +6 more
wiley +1 more source
The Lysosomal Clock: Are We Only as Old as Our Lysosomes? [PDF]
Vegas AD, Galli T.
europepmc +1 more source
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
Two-stage cooperative optimisation of signal timing and vehicle trajectories for eco-driving at signalised intersections under HDV/CAV/CCAV mixed traffic. [PDF]
Wen R +5 more
europepmc +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source

