Results 31 to 40 of about 613,794 (269)

Netml-ns3-click: Modeling of Routers in Netml/ns3 by means of the Click Modular Router

EAI Endorsed Transactions on Mobile Communications and Applications, 2016
In this paper the design, development and use of a facility to run ns3 simulations, including Click routers, of networks constructed by the Netml system for analysis and design of networks in the cloud is described.
Ronald Addie, Joshua Natarajan
doaj   +1 more source

Ways to go? (Un)sustainable school commuting in Majorna, Gothenburg city

International Journal of Urban Sustainable Development, 2023
Gothenburg city has bold ambitions of becoming carbon neutral. School commuting is one piece of the puzzle in reducing emissions. While the literature on school transportation is extensive, the issue of climate change has been overlooked.
Beniamin Knutsson, Sofie Hellberg
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Estimation of Traffic Matrices for LRD Traffic

, 2012
The estimation of traffic matrices in a communications network on the basis of a set of traffic measurements on the network links is a well-known problem, for which a number of solutions have been proposed when the traffic does not show dependence over time, as in the case of the Poisson process.
P. L. Conti, DE GIOVANNI, LIVIA, M. Naldi   +2 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Fuzzy renewal theory about forecasting mistakes done by a locomotive driver: a serbian railway case study

Transport, 2012
The human factor is one of the most dominant causes of railway accidents. For example, human impact appears to be the main reason for 44% of railway accidents in the Republic of Serbia. Thus, a remarkable effort is undertaken to investigate human factors.
Milan Marković, Norbert Pavlović, Miloš Ivić   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Nautical traffic simulation with multi-agent system

, 2013
This paper describes a microscopic nautical traffic simulation model based on multi-agent system. The ship traffic is produced from the behavior of autonomous agents that represent ships.
Coen van Gulijk, Han Ligteringen, Fangliang Xiao, Van Gulijk, Coen, Ale, B.J.M. (author), Ale, B. (author), Ale, B.J.M., Ligteringen, H. (author), Van Gulijk, C. (author), Xiao, F. (author), Ligteringen, Han, Van Gulijk, C., Xiao, F., Ben Ale, Xiao, Fangliang, Ale, Ben, Ligteringen, H.   +16 more
core   +1 more source