Results 31 to 40 of about 1,136,484 (306)

An Integrated Data-Driven Predictive Resilience Framework for Disaster Evacuation Traffic Management

open access: yesApplied Sciences, 2023
Maintaining smooth traffic during disaster evacuation is a lifesaving step. Traffic resilience is often used to define the ability of a roadway during disaster evacuation to withstand and recover its functionality from disturbances in terms of traffic ...
Tanzina Afrin   +3 more
doaj   +1 more source

Spatial analysis of transport noise in Hit City [PDF]

open access: yesمجلة جامعة الأنبار للعلوم الإنسانية
Objectives: The noise intensity emitted by transportation vehicles in the city of Hit was measured, and for all the city's neighborhoods at specific points (5) m away from the noise source and for a period of (2) minutes. The measurement was made using a
Hanan Al-khalidy, Qusai Hussein
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ways to go? (Un)sustainable school commuting in Majorna, Gothenburg city

open access: yesInternational Journal of Urban Sustainable Development, 2023
Gothenburg city has bold ambitions of becoming carbon neutral. School commuting is one piece of the puzzle in reducing emissions. While the literature on school transportation is extensive, the issue of climate change has been overlooked.
Beniamin Knutsson, Sofie Hellberg
doaj   +1 more source

Estimation of Traffic Matrices for LRD Traffic

open access: yes, 2012
The estimation of traffic matrices in a communications network on the basis of a set of traffic measurements on the network links is a well-known problem, for which a number of solutions have been proposed when the traffic does not show dependence over time, as in the case of the Poisson process.
P. L. Conti   +2 more
openaire   +3 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Traffic control signal design manual

open access: yes, 2009
Title from PDF cover (DOT web site, viewed Dec. 3, 2009).; Previously published: Manual of traffic control signal design. [Wethersfield, Conn] : Dept. of Transportation, Bureau of Highways, Office of Engineering, Division of Traffic, [1984].; Includes ...

core   +1 more source

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