Results 91 to 100 of about 7,816,845 (321)

Dynamic Analyses on Network Traffic Flow

INFRASTRUCTURE PLANNING REVIEW, 1999
This paper summarizes dynamic network analyses utilizing cumulative arrival and departure curves under point as well as physical queues. First, a relationship between the cumulative curve under point and physical queue concepts and time-space diagram is explained.
openaire   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Increasing resilience of ATM networks using traffic monitoring and automated anomaly analysis [PDF]

, 2012
Systematic network monitoring can be the cornerstone for the dependable operation of safety-critical distributed systems. In this paper, we present our vision for informed anomaly detection through network monitoring and resilience measurements to ...
Johnson, Christopher W., Pezaros, Dimitrios P., White, Kyel .J.S.   +2 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Levels, sources and seasonality of coarse particles (PM10-PM2.5) in three European capitals e implications for particulate pollution control [PDF]

, 2012
Coarse particles of aerodynamic diameter between 2.5 and 10 mm (PMc) are produced by a range of natural (windblown dust and sea sprays) and anthropogenic processes (non-exhaust vehicle emissions, industrial, agriculture, construction and quarrying ...
Borge, R, Chaloulakou, A, Grivas, G, Kassomenos, P, Lumbreras, J, Vardoulakis, S   +5 more
core   +3 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Reasoned modelling critics: turning failed proofs into modelling guidance

, 2011
The activities of formal modelling and reasoning are closely related. But while the rigour of building formal models brings significant benefits, formal reasoning remains a major barrier to the wider acceptance of formalism within design. Here we propose
Abrial, Abrial, Abrial, Andrew Ireland, Barrett, Brown, Bundy, Bundy, Bundy, Butler, Dixon, Gamma, Gudmund Grov, Ireland, Ireland, Ireland, Leuschel, Maria Teresa Llano, Michael Butler, Monroy   +19 more
core   +1 more source

Analyses of Real Email Traffic Properties

Radioengineering, 2009
In this paper, we perform an empirical analysis of email traffic logs obtained from a large university to better understand its impact on the effectiveness and efficiency of anonymous mix remailers. We analyzed data containing records of almost 790,000 emails sent over a period of forty days – the largest dataset we are aware of.
Malinka, Kamil, Hanacek, Petr, Cvrcek, Dan   +2 more
openaire   +2 more sources