Results 61 to 70 of about 7,816,845 (321)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Using principal curves to analyse traffic patterns on freeways [PDF]

Transportmetrica, 2011
Scatterplots of traffic speed versus flow have received considerable attention over the past decades due to their characteristic half-moon shape. Modelling data of this type is difficult as both variables are actually not a function of each other in the sense of causality, but are rather jointly generated by a third latent variable, which is a monotone
Einbeck, Jochen, Dwyer, Jo
openaire   +3 more sources

Deep Learning Algorithms for Traffic Forecasting: A Comprehensive Review and Comparison with Classical Ones

Journal of Advanced Transportation
Accurate and timely forecasting of critical components is pivotal in intelligent transportation systems and traffic management, crucially mitigating congestion and enhancing safety.
Shahriar Afandizadeh Zargari, Saeid Abdolahi, H. Mirzahossein   +2 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An In Depth Study into Using EMI Signatures for Appliance Identification

, 2014
Energy conservation is a key factor towards long term energy sustainability. Real-time end user energy feedback, using disaggregated electric load composition, can play a pivotal role in motivating consumers towards energy conservation. Recent works have
Jain M., Lee W., Leeb S. B., Parson O., Paul C. R., Russell M. J., Shaw S. R., Zoha A.   +7 more
core   +1 more source

Analysing traffic flows through sampling: A comparative study

2015 IEEE Symposium on Computers and Communication (ISCC), 2015
Understanding network workload through the characterization of network flows, being essential for assisting network management tasks, can benefit largely from traffic sampling as long as an accurate snapshot of network behavior is captured. This paper is devoted to evaluate the real applicability of using sampling to support flow analysis.
Silva, Joao Marco C., Carvalho, Paulo, Lima, Solange   +2 more
openaire   +3 more sources

Crowdsourced air traffic data from the OpenSky Network 2019–2020

Earth System Science Data, 2020
. The OpenSky Network is a non-profit association that crowdsources the global collection of live air traffic control data broadcast by aircraft and makes them available to researchers.
Martin Strohmeier, X. Olive, Jannis Lübbe, Matthias Schäfer, Vincent Lenders   +4 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Single-Board-Computer Clusters for Cloudlet Computing in Internet of Things [PDF]

, 2019
The number of connected sensors and devices is expected to increase to billions in the near future. However, centralised cloud-computing data centres present various challenges to meet the requirements inherent to Internet of Things (IoT) workloads ...
Fernández Cerero, Damián, Fernández Rodríguez, Jorge Yago, Fernández-Montes González, Alejandro, Soria Morillo, Luis Miguel, Álvarez García, Juan Antonio   +4 more
core   +1 more source