Results 81 to 90 of about 7,816,845 (321)

Relationship Between Traffic Volume and Accident Frequency at Intersections

International Journal of Environmental Research and Public Health, 2020
Driven by the high social costs and emotional trauma that result from traffic accidents around the world, research into understanding the factors that influence accident occurrence is critical.
A. Retallack, B. Ostendorf
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Analysing Traffic Flow and Traffic Hotspots from Historic and Real-Time GPS Data [PDF]

Journal of Communication and Computer, 2015
Traffic congestion is an increasing issue in many road networks. Considering the Maltese Islands, the traffic situation is in bad condition, despite the different attempts by the government to find a solution for this problem. In this report, we investigate how traffic may be analysed, which methods are available for this analysis, and how the traffic ...
null Christopher Bartolo, null Thiago Matos Pinto   +1 more
openaire   +1 more source

Effect of Road Traffic on Air Pollution. Experimental Evidence from COVID-19 Lockdown

Sustainability, 2020
The increasing concentration of human activities in cities has been leading to a worsening in air quality, thus negatively affecting the lives and health of humans living in urban contexts.
R. Rossi, Riccardo Ceccato, Massimiliano Gastaldi   +2 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

MERCURY IN ATMOSPHERE OVER RURAL, URBAN AND INDUSTRIAL PARTS OF ZAGREB CITY

Rudarsko-geološko-naftni Zbornik, 1990
In recent years Zagreb city encounters severe pollution problems in aquatic, terrrestrial and atmospheric environment. A random or permanent monitoring of some inorganic gaseous pollutants in atmosphere has already been organized and published alsewhere.
Ladislav A. Palinkaš, Sergej E. Sholupov , Nikolai R. Mashyanov , Goran Durn, Slobodan Miko   +4 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effects of an on line bypass oil recycler on emissions with oil age for a bus using in service testing [PDF]

, 2001
A method of cleaning lubricating oil on line was investigated using a fine bypass particulate filter followed by an infra red heater. Two bypass filter sizes of 6 and 1 micron were investigated, both filter sizes were effective but the one micron ...
Andrews, G.E., Hall, J., Li, H., Mawson, P., Rahman, A.A.   +4 more
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source