Results 61 to 70 of about 25,989,787 (296)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Real-Time Traffic Analysis using Deep Learning Techniques and UAV based Video
Advanced Video and Signal Based Surveillance, 2019 In urban environments there are daily issues of traffic congestion which city authorities need to address. Realtime analysis of traffic flow information is crucial for efficiently managing urban traffic.
Huaizhong Zhang +3 more
semanticscholar +1 more source
Chinese MedicineTreatment planning for chronic diseases is a critical task in medical artificial intelligence, particularly in traditional Chinese medicine (TCM).
Kuo Yang +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Big Data Mining and AnalyticsGiven the explosive growth in video content generation, there is a rising demand for efficient and scalable video recognition. Deep learning has shown its remarkable performance in video analytics, by applying 2D or 3D Convolutional Neural Networks (CNNs)
Qingli Wang +4 more
doaj +1 more source
Understanding Sputnik News Agency Internet Traffic Analysis
Bulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law, 2020 Sputnik news agency remains one of the main channels used by Russia to conduct disinformation campaigns across its borders, affecting both Romania and the Republic of Moldova virtual communities.
Bogdan Gabriel Stefan
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Understanding the multi-mass model and sound generation of vocal fold oscillation
AIP Advances, 2019 When a speaker speaks, the vocal fold oscillates, generating a voice. The voice resonating in the vocal tract and in the mouth is converted to speech when the speaker changes the shapes of the mouth and tongue.
Myung-cheol Park
doaj +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source