Results 101 to 110 of about 1,316,228 (290)

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

Advanced Science, EarlyView.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang, Renming Fan, Yongrui Hai, Ye Chen, Xintong Lu, Wenhui Wang, Jiarui Dou, Jiaxin Yan, Chang Su, Yue Chen, Le Yang, Minggao Zhao, Lei Liang, Gaofei Wei   +13 more
wiley   +1 more source

Machine-Learned Prediction Equilibrium for Dynamic Traffic Assignment [PDF]

, 2021
Lukas Graf, Tobias Harks, Kostas Kollias, Michael Markl   +3 more
openalex   +1 more source

Static traffic assignment with residual queues and spillback

Transportation Research Part B: Methodological, 2020
M. Bliemer, M. P. Raadsen
semanticscholar   +1 more source

Impact of Static Urban Traffic Flow-Based Traffic Weighted Multi-Maps Routing Strategies on Pollutant Emissions

Systems
Addressing urban traffic congestion is a pressing issue requiring efficient solutions that need to be analyzed regarding travel time and pollutant emissions.
Alvaro Paricio-Garcia, Miguel A. Lopez-Carmona   +1 more
doaj   +1 more source

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

Quantifying road traffic emissions embedded in a multi-objective traffic assignment model

Transportation Research Procedia, 2020
Eloísa Macedo, Ricardo Tomás, P. Fernandes, M. Coelho, J. Bandeira   +4 more
semanticscholar   +1 more source

Comparison of traffic assignment in VISUM and transport simulation in MATSim [PDF]

Transport Problems, 2013
The paper presents a comparison of different approaches to traffic modelling and forecasting in VISUM and MATSim. The comparison was based on three indicators: link volumes, average travel time and distance.
Bartłomiej PIĄTKOWSKI, Michał MACIEJEWSKI   +1 more
doaj  

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

Devices, Functions, and Applications of Artificial Neuromorphic Visual Systems

Advanced Science, EarlyView.
This review highlights recent advances in optoelectronic synapses for artificial neuromorphic vision, emphasizing their material systems, structural designs, and performance metrics. It further discusses visual neural networks enabled by these synapses, covering perception, memory, and recognition functionalities, and analyzes challenges in stability ...
Jiaxin Liu, Bo Li, Chi Liu, Dongming Sun, Huiming Cheng   +4 more
wiley   +1 more source

THEORY OF TRAFFIC ASSIGNMENT THROUGH ABSORBING MARKOV PROCESS

, 1965
Tsuna Sasaki
openalex   +2 more sources