Results 41 to 50 of about 1,316,228 (290)
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study explores the benefits of metasurfaces made from functional materials, highlighting their ability to be adapted and improved for various high‐frequency applications, including communications and sensing. It first demonstrates the potential of these functional material‐based metasurfaces to advance the field of sub‐THz perceptive networks ...
Yat‐Sing To +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin +14 more
wiley +1 more source
Research on enhanced channel assignment scheme in wireless mesh network
Tongxin xuebao, 2012 To ensure the reliability of the wireless mesh network resource assignment,an interference model to node traffic model of WMN was introduced,and channel assignment strategy based on fixed traffic-awareness C-HYA channel assignment strategy was improved ...
Lin-han FENG +2 more
doaj +2 more sources
Journal of Advanced Transportation, 2018 This paper examines the impact of applying dynamic traffic assignment (DTA) and quasi-dynamic traffic assignment (QDTA) models, which apply different route choice approaches (shortest paths based on current travel times, User Equilibrium: UE, and system ...
Marialisa Nigro +5 more
doaj +1 more source
Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering
Advanced Healthcare Materials, EarlyView.This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer +4 more
wiley +1 more source
Energy Consumption Optimization in Trajectory Planning for Fuel Cell Hybrid Uavs Based On HMPC
Advanced Robotics Research, EarlyView.The endurance limitation of multirotor drones is a critical challenge. This study adopts a hybrid power system of fuel cells and lithium‐ion batteries. Using Nondominated Sorting Genetic Algorithm II, it integrates trajectory planning with energy management optimization.
Xindi Wang +7 more
wiley +1 more source
Differential Game Modeling Approach to Dynamic Traffic Assignment and Signal Control
European Journal of Transport and Infrastructure Research, 2003 This paper addresses a theoretical issue related to combined dynamic traffic assignment and signal control under conditions of congestion through a brief review of previous research and the discussion on interaction between dynamic traffic assignment and
Zhenlong Li, Songquan Shi
doaj +1 more source
Advanced Science, EarlyView.The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source
Average Bandwidth Allocation Model of WFQ
Modelling and Simulation in Engineering, 2012 We present a new iterative method for the calculation of average bandwidth assignment to traffic flows using a WFQ scheduler in IP based NGN networks. The bandwidth assignment calculation is based on the link speed, assigned weights, arrival rate, and ...
Tomáš Balogh, Martin Medvecký
doaj +1 more source