Results 51 to 60 of about 17,015 (310)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

A Day-to-Day Stochastic Traffic Flow Assignment Model Based on Mixed Regulation

IEEE Access, 2020
In many cases, the final path selection of travellers' is not the shortest path, due to the limited computing power and high cost of path search. To solve the problem, this paper proposes a day-to-day (DTD) stochastic traffic flow assignment model that ...
Lixuan Wu, Zhongxiang Huang, Jianhui Wu, Zhibo Gao, Dingming Qin   +4 more
doaj   +1 more source

Synergistic Traffic Assignment

Traffic assignment analyzes traffic flows in road networks that emerge due to traveler interaction. Traditionally, travelers are assumed to use private cars, so road costs grow with the number of users due to congestion. However, in sustainable transit systems, travelers share vehicles s.t.
Bläsius, Thomas, Feilhauer, Adrian, Jung, Markus, Laupichler, Moritz, Sanders, Peter, Zündorf, Michael   +5 more
openaire   +2 more sources

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

A model of air traffic assignment as part of airport air pollution management system / Oro transporto paskirstymo modelis oro uosto oro taršos valdymo sistemoje

Aviation, 2012
The critical concern of modern airports is the air pollution generated by air traffic and its impact on the airport environment. Air pollution is an unavoidable consequence of air traffic, but it can be reduced in numerous ways, including technical ...
Petar Mirosavljević, Slobodan Gvozdenović, Olja Čokorilo   +2 more
doaj   +1 more source

Energy Consumption Optimization in Trajectory Planning for Fuel Cell Hybrid Uavs Based On HMPC

Advanced Robotics Research, EarlyView.
The endurance limitation of multirotor drones is a critical challenge. This study adopts a hybrid power system of fuel cells and lithium‐ion batteries. Using Nondominated Sorting Genetic Algorithm II, it integrates trajectory planning with energy management optimization.
Xindi Wang, Jianyang Dong, Yongming Yao, Kaijin Hu, Jianxiong Cui, Yikai Luo, Jiawen Zhang, Shichao Niu   +7 more
wiley   +1 more source

Effects of Anticipatory Control with Multiple User Classes

European Journal of Transport and Infrastructure Research, 2003
In this paper the integrated traffic control and traffic assignment problem is studied. This problem can be considered as a non-cooperative game in which the traffic authority, that controls the traffic signals, and the road users are the players, who ...
Henk Taale, Henk van Zuylen
doaj   +1 more source

Challenges and Future Directions in Assessing the Quality and Completeness of Advanced Materials Safety Data for Re‐Usability: A Position Paper From the Nanosafety Community

Advanced Sustainable Systems, EarlyView.
Nanosafety data provide a guiding example for establishing best practices in data management, aligning with FAIR principles and quality criteria. This review explores existing quality assessment approaches for reliability, relevance, and completeness, emphasizing the need for harmonization and adaptation to nanomaterials and advanced materials. The aim
Verónica I. Dumit, Irini Furxhi, Penny Nymark, Antreas Afantitis, Ammar Ammar, Monica J. B. Amorim, Dalila Antunes, Svetlana Avramova, Chiara L. Battistelli, Gianpietro Basei, Cecilia Bossa, Emil Cimpan, Mihaela Roxana Cimpan, Dmitri Ciornii, Anna Costa, Camilla Delpivo, Maria Dusinska, Ana Sofia Fonseca, Steffi Friedrichs, Vasile‐Dan Hodoroaba, Danail Hristozov, Panagiotis Isigonis, Nina Jeliazkova, Nikolay Kochev, Eva Kranjc, Dieter Maier, Georgia Melagraki, Anastasios G. Papadiamantis, Tomasz Puzyn, Hubert Rauscher, Katie Reilly, Araceli Sánchez Jiménez, Janeck J. Scott‐Fordsmand, Neeraj Shandilya, Hyun Kil Shin, Gergana Tancheva, Jeaphianne P. M. van Rijn, Egon L. Willighagen, Ewelina Wyrzykowska, Martine I. Bakker, Damjana Drobne, Thomas E. Exner, Martin Himly, Iseult Lynch   +43 more
wiley   +1 more source

INTEGRATION Framework for Modeling Eco-routing Strategies: Logic and Preliminary Results

International Journal of Transportation Science and Technology, 2012
The paper presents the INTEGRATION microscopic traffic assignment and simulation framework for modeling eco-routing strategies. Two eco-routing algorithms are developed: one based on vehicle sub-populations (ECO-Subpopulation Feedback Assignment or ECO ...
Hesham A. Rakha
doaj   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source