Results 81 to 90 of about 1,502,044 (367)

Modelling the Choice of Car Parks in Urban Areas and Managing the Demand for Parking. [PDF]

, 2008
Car parks are an essential piece of infrastructure associated with the road networks, yet commonly available traffic assignment models do not to explicitly integrate them into the modelling process. This research attempts to integrate the choice of car
Balijepalli, N.C., May, A.D., Shepherd, S.P.   +2 more
core  

Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer

Advanced Science, EarlyView.
Dysregulated RNA splicing is an underappreciated molecular feature of cancer. By integrating murine and cellular models with patient specimens of lung adenocarcinoma, this study demonstrates that RAC1B, rather than RAC1A isoform, promotes tumorigenesis and presents a potent therapeutic target for lung cancer. Mechanistically, RAC1B preferentially binds
Yueren Yan, Ning Wang, Bowen Xing, Min Yang, Jun Shang, Yufang Bao, Lixing Xiao, Ningxia Zhang, Yunpeng Ren, Chunnan Liu, Yuting Chen, Han Han, Yunjian Pan, Lei Lv, Wei‐Xing Zong, Hongbin Ji, Changyou Zhan, Zefeng Wang, Haiquan Chen, Yongbo Wang   +19 more
wiley   +1 more source

Distributed Dynamic Traffic Modeling and Implementation Oriented Different Levels of Induced Travelers

Discrete Dynamics in Nature and Society, 2015
In order to respond to the variable state of traffic network in time, a distributed dynamic traffic assignment strategy is proposed which can improve the intelligent traffic management.
Yan Liu, Yao Yu
doaj   +1 more source

INTEGRATION Framework for Modeling Eco-routing Strategies: Logic and Preliminary Results

International Journal of Transportation Science and Technology, 2012
The paper presents the INTEGRATION microscopic traffic assignment and simulation framework for modeling eco-routing strategies. Two eco-routing algorithms are developed: one based on vehicle sub-populations (ECO-Subpopulation Feedback Assignment or ECO ...
Hesham A. Rakha
doaj   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Advanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma   +8 more
wiley   +1 more source

How realistic is static traffic assignment? Analyzing automatic number-plate recognition data and image processing of real-time traffic maps for investigation

Transportation Research Interdisciplinary Perspectives, 2021
Travel demand information in the form of the origin–destination (OD) matrix plays an essential role in studying urban traffic management and network design. The present study takes a novel step toward urban traffic analysis using data mining of processed
Hamid Mirzahossein, Iman Gholampour, Maryam Sedghi, Lei Zhu   +3 more
doaj  

Multi-class dynamic traffic assignment with physical queues: intersection-movement-based formulation and paradox

, 2016
This paper proposes an intersection-movement-based variational inequality formulation for the multi-class dynamic traffic assignment (DTA) problem involving physical queues using the concept of approach proportion.
Yu Jiang, W. Y. Szeto, J. Long, Ke Han
semanticscholar   +1 more source

Dynamic User Equilibrium (DUE) [PDF]

, 2006
The quantitative analysis of road network traffic performed through static assignment models yields the transport demand-supply equilibrium under the assumption of within-day stationarity.
GENTILE, Guido, K. NOEKEL, MESCHINI, LORENZO   +2 more
core   +1 more source

Sequence‐ and Docking‐Site‐Dependent Contributions to Multi‐Site Phosphorylation of an Intrinsically Disordered MAPK Substrate

Advanced Science, EarlyView.
Real‐time NMR spectroscopy is used to study JNK1‐dependent phosphorylation of the intrinsically disordered substrate JIP1, revealing eleven phosphosites with distinct phosphorylation efficiencies. The site‐specific phosphorylation rates are shown to be determined by both the sequence position of the phosphosites relative to the two kinase docking site ...
Thibault Orand, Elise Delaforge, Marion Chenal, Maud Tengo, Torsten Herrmann, Juan Cortés, Pau Bernadó, Malene Ringkjøbing Jensen   +7 more
wiley   +1 more source

Effects of Anticipatory Control with Multiple User Classes

European Journal of Transport and Infrastructure Research, 2003
In this paper the integrated traffic control and traffic assignment problem is studied. This problem can be considered as a non-cooperative game in which the traffic authority, that controls the traffic signals, and the road users are the players, who ...
Henk Taale, Henk van Zuylen
doaj   +1 more source