Results 171 to 180 of about 3,911,620 (341)

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

open access: yesAdvanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li   +11 more
wiley   +1 more source

Lightweight, Payload-Based Traffic Classification: An Experimental Evaluation [PDF]

open access: yes, 2008
Baldi, Mario   +4 more
core   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

Giant Switchable Remanent Polarization and Photocurrent in Ferroelectric Thin Film Photomemristor for In Situ Training

open access: yesAdvanced Science, EarlyView.
The device exhibits excellent ferroelectric performance and significant photoelectric response. It can adapt to light stimuli of varying power and wavelengths while achieving a stable and tunable photovoltaic response state. Moreover, the device can utilize photoconductive states of different directions and magnitudes to achieve pattern classification ...
Zhen Zhao   +21 more
wiley   +1 more source

Traffic Sign Classification Using CNN

open access: yesINTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
This study presents a novel approach for traffic sign classification leveraging Convolutional Neural Networks (CNNs). With the proliferation of autonomous vehicles and advanced driver assistance systems, accurate and efficient traffic sign recognition is imperative for safe and efficient navigation.
openaire   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

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