Results 41 to 50 of about 101,188 (264)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

FleetPy: an open source simulator for reproducible research on mobility-on-demand services

European Transport Research Review
Mobility-on-demand (MoD) services have been extensively investigated across multiple research disciplines. For example, transport planners are interested in the impact on mode choice and traffic, while researchers in operations research focus on ...
Roman Engelhardt, Florian Dandl, Arslan Ali Syed, Chenhao Ding, Santiago Alvarez-Ossorio Martinez, Yunfei Zhang, Hoda Hamdy, Joel Brodersen, Zhipu Chen, Klaus Bogenberger   +9 more
doaj   +1 more source

A Train Positioning Error Estimation Method Suitable for Multiple Trains Virtual Marshalling Control System

Chengshi guidao jiaotong yanjiu
Objective Virtual marshalling technology requires high precision and accuracy of train positioning, and traditional train positioning technologies are unable to meet the safety requirements of the virtual marshalling SIL4.
FAN Ying, WEN Bowei, WANG Zhizhuo
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Some aspects of traffic control and performance evaluation of ATM networks [PDF]

, 1997
The emerging high-speed Asynchronous Transfer Mode (ATM) networks are expected to integrate through statistical multiplexing large numbers of traffic sources having a broad range of statistical characteristics and different Quality of Service (QOS ...
Fan, Zhong, Fan, Z.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Lowering traffic without sacrificing performance in networked control systems [PDF]

, 2011
In Networked Control Systems (NCS), the amount of control data exchanged between sensors, controllers and actuators nodes highly depends on the control performance specifications given to each networked control loop.
Martín Rull, Enric Xavier, Manel Velasco, Yépez Castillo, José Gregorio, Enric X. Martin, Pau Marti, Jose Yepez, Velasco García, Manel, Martí Colom, Pau   +7 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Utility Evaluation of Compartment Service Configuration Based on Kano Model

Chengshi guidao jiaotong yanjiu
Objective Aiming at enhancing the comprehensive experience for passengers during travel, it is necessary to investigate and analyze compartment service demands, optimize compartment service facility configurations.
Xinde MAO, Ziyue YAN, Yingjie LIU
doaj   +1 more source