Results 31 to 40 of about 8,974,401 (286)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Towards a benchmarking of Microscopic Traffic Flow Models [PDF]
, 2003 Several microscopic traffic models have been tested with a publicly available data set. The task was to predict the travel times between sever observers along a one-lane rural road, given as boundary conditions the flow into this road and the flow out of
Brockfeld, Elmar +3 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
DEVELOPMENT OF A VESSEL TRAFFIC SIMULATION SYSTEM
International Journal of Advanced Studies, 2021 This report is devoted to the consideration of the process of modeling vessel traffic. The meaning of the term traffic flow in the theory and practice of navigation is revealed in detail. Particular attention is paid to the creation of a computer program
Anastasia Fedorovna Shvetsova
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Calibration and Validation of Microscopic Traffic Flow Models [PDF]
, 2004 Microscopic simulation models are becoming increasingly important tools in modeling transport systems. There are a large number of available models used in many countries.
Brockfeld, Elmar +2 more
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Bayesian Calibration of Traffic Flow Fundamental Diagrams Using Gaussian Processes
IEEE Open Journal of Intelligent Transportation Systems, 2022 Modeling the relationship between vehicle speed and density on the road is a fundamental problem in traffic flow theory. Recent research found that using the least-squares (LS) method to calibrate single-regime speed-density models is biased because of ...
Zhanhong Cheng +4 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Road Traffic Anomaly Detection Based on Fuzzy Theory
IEEE Access, 2018 The road traffic scenes are usually complex and the traffic video is vulnerable to external factors such as light, weather, and obstructions. It is difficult to extract the traffic parameters and detect the traffic anomaly exactly with the existing image
Yanshan Li +3 more
doaj +1 more source