Results 141 to 150 of about 1,059,013 (343)

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

A review on air traffic flow management optimization: trends, challenges, and future directions [PDF]

open access: gold
Verma Aditya   +5 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

The Speaker Identification Model for Air-Ground Communication Based on a Parallel Branch Architecture

open access: yesApplied Sciences
This study addresses the challenges of complex noise and short speech in civil aviation air-ground communication scenarios and proposes a novel speaker identification model, Chrono-ECAPA-TDNN (CET).
Weijun Pan   +4 more
doaj   +1 more source

Air traffic control by distributed management in a MLS environment [PDF]

open access: yes
The microwave landing system (MLS) is a technically feasible means for increasing runway capacity since it could support curved approaches to a short final.
Hart, S., Kreifeldt, J. G., Parkin, L.
core   +1 more source

The influence of traffic management at a regulated intersection on the uniformity of traffic capacity

open access: diamond, 2020
Roman Andronov   +3 more
openalex   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

open access: yesAdvanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu   +17 more
wiley   +1 more source

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