Results 251 to 260 of about 2,719,537 (351)

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

open access: yesiMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang   +16 more
wiley   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

open access: yesiMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou   +8 more
wiley   +1 more source

Road traffic noise and breast cancer: DNA methylation in four core circadian genes. [PDF]

open access: yesClin Epigenetics
Thacher JD   +9 more
europepmc   +1 more source

Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Classical approaches for coloration analysis are limited by human low‐resolution phenotyping and genetic analysis. Artificial intelligence allows us to find genes beyond the tip of the iceberg that explain color and pattern diversity in nature. ABSTRACT Pigmentation has long served as a powerful system for exploring gene–trait relationships, yet much ...
Ehsan Pashay Ahi, Nidal Karagic
wiley   +1 more source

Outdoor air pollution, road traffic noise, and allostatic load in children aged 6-11 years: evidence from six European cohorts. [PDF]

open access: yesEur J Epidemiol
Mou Y   +19 more
europepmc   +1 more source

A randomized trial of I‐SLEEP: A patient education and empowerment intervention on inpatient sleep duration and medical sleep disruptions

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Sleep is essential for recovery in hospitalized patients, yet frequent disruptions from medical care make rest difficult. Most prior efforts have focused on environmental modifications, often overlooking patients' role in advocating for their sleep.
Aashna Sunderrajan   +10 more
wiley   +1 more source

Impact of 1024‐Matrix Size on Perforating Artery Visualisation in Cerebral Computed Tomography Angiography Using a 64‐Slice CT Scanner

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This study investigated whether using a larger image matrix (1024 × 1024 pixels instead of 512 × 512) improves the visibility of tiny brain arteries on CT scans performed with standard 64‐slice scanners. While physical image quality measurements remained unchanged, the larger matrix provided finer digital sampling of blood vessel structures, resulting ...
Hokuto Nagumo   +5 more
wiley   +1 more source

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