Results 161 to 170 of about 31,722 (259)

Influence of Traffic Input Data Quality on Road Noise Estimates Using the CNOSSOS-EU Method. [PDF]

open access: yesSensors (Basel)
Ascari E   +7 more
europepmc   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta   +26 more
wiley   +1 more source

Rest‐activity patterns across development in two mouse models of autism and epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash   +4 more
wiley   +1 more source

A Review of Energy Management Strategies for Hybrid Electric Vehicles

open access: yesEnergy Science &Engineering, EarlyView.
This review systematically categorizes energy management strategies (EMS) for hybrid electric vehicles, highlighting rule‐based, optimization‐based, learning‐based, and emerging algorithm‐mixing approaches. It provides a comprehensive roadmap for developing intelligent control systems to enhance energy efficiency and promote sustainable transportation.
Song Gao   +9 more
wiley   +1 more source

Quadruplex Bioactive FAND for Treating Acute Liver Failure Induced by Acetaminophen or Hepatectomy

open access: yesExploration, EarlyView.
This work developed a bioactive quadruplex FANDHP@FuEVs with intrinsic inflammation‐targeting properties of M2‐EVs and MSC‐EVs, harnessing the synergistic biological activities by leveraging four natural active components—M2‐EVs, MSC‐EVs, HGF, and PPC—to deliver pleiotropic therapies, including antioxidant, anti‐inflammatory, pro‐regenerative, and M1 ...
Meng Sun   +10 more
wiley   +1 more source

Monitoring and assessment for obstructive sleep apnea

open access: yesFlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu   +6 more
wiley   +1 more source

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