Results 11 to 20 of about 234 (93)

Integrating noise as a risk factor in studies of Alzheimer's disease and dementia: Guidance for epidemiologic research. [PDF]

Alzheimers Dement
Abstract Noise exposure is increasingly recognized as a modifiable environmental risk factor for Alzheimer's disease and related dementias (ADRD), yet its integration into epidemiologic research remains limited. We reviewed international noise mapping resources, exposure metrics, and analytic approaches relevant to ADRD studies.
Bozigar M, Weuve J, Clark SN, Grady ST, Cantuaria ML, Cai YS, Roscoe C, Röösli M, Peters JL, Seto E, Vienneau D, Sørensen M, Neitzel RL, Hastings AL, Luben TJ, Andersen ZJ, Clark C, Hansell AL, Hystad P, Brauer M, Adar SD.   +20 more
europepmc   +2 more sources

APB-FLDPA: Adaptive Personalized Blockchain-Federated Learning With Differential Privacy and Attention for Privacy-Preserving Healthcare Analytics. [PDF]

Healthc Technol Lett
We propose APB‐FLDPA, an adaptive and privacy‐preserving federated learning framework for multi‐institutional healthcare analytics that integrates Byzantine‐resilient aggregation, selective differential privacy, attention‐based feature earning, personalization, and blockchain‐based auditability.
Chowdhury MKH, Mondal PK, Mozumder MAI, Kim HC, Byeon H.   +4 more
europepmc   +2 more sources

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +3 more sources

Interferon‐induced transmembrane (IFITM) proteins at the tumour–immune interface: A four‐axis framework for their context‐dependent roles

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Interferon‐induced transmembrane (IFITM) function in cancer is set by four contextual coordinates, not by family membership. Acute interferon input drives major histocompatibility complex class I (MHC‐I)‐linked immunogenicity; chronic input drives programmed death‐ligand 1 (PD‐L1)‐coupled resistance.
Zhe Liu, Jie Meng, Zengyan Lai, Fuqiu Li, Sha Lv   +4 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, Volume 20, Issue 7, Page 1857-1876, July 2026.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Multiomics Research Strategies in Cancer: A Growing and Innovative Field

MedComm, Volume 7, Issue 4, April 2026.
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du, Xiaomei Liu, Zhi Lv, Bengang Wang, Yu Xia, Wala Abduljabbar Mohammed Al‐Duais, Lirong Yan, Fuqiang Zhang, Yanke Li   +8 more
wiley   +1 more source

Role of N‐glycosylation as a determinant of ATG9A conformations and activity

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Here, we investigate the effects of glycosylation at position N99 on the structural dynamics and lipid scrambling activity of ATG9A, a key autophagy protein, using microsecond all‐atom molecular dynamics simulations. ATG9A is an integral membrane protein involved in autophagosome biogenesis, and glycosylation at N99 has previously been ...
Mattia Utichi, Matteo Lambrughi, Henri‐Baptiste Marjault, Christian B. Borg, Sergio Esteban Echeverría, Kenji Maeda, Nicholas M. I. Taylor, Anders Gorm Pedersen, Elisa Fadda, Marja Jäättelä, Elena Papaleo   +10 more
wiley   +1 more source

Immunometabolic Features and Key Biomarkers in Lung Cancer Complicated by Pulmonary Tuberculosis: Insights From Transcriptome and Clinical Cohort Analysis

iMetaMed, Volume 1, Issue 2, December 2025.
Integrative analysis of LC‐PTB patients pinpoints six biomarkers (ANK2, EPB42, CA1, HBB, HBD, MYL4) that reshape the immune microenvironment, offering new targets for diagnosis and treatment of lung cancer complicated by tuberculosis. ABSTRACT Coexisting lung cancer and pulmonary tuberculosis (LC‐PTB) is clinically challenging in diagnosis and ...
Ling Yang, Shanshan Li, Guangliang Bai, Longyan Li, Yuxi Li, Xuejiao Liang, Zhaoyang Ye, Linsheng Li, Li Zhuang, Jingzhi Guan, Wenping Gong   +10 more
wiley   +1 more source