Results 41 to 50 of about 359,562 (287)

Prediction feedback in intelligent traffic systems

open access: yes, 2009
The optimal information feedback has a significant effect on many socioeconomic systems like stock market and traffic systems aiming to make full use of resources. In this paper, we studied dynamics of traffic flow with real-time information provided and
Arnott   +26 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Improving adaptation and interpretability of a short-term traffic forecasting system [PDF]

open access: yes, 2017
Traffic management is being more important than ever, especially in overcrowded big cities with over-pollution problems and with new unprecedented mobility changes.
Casas Vilaró, Jordi   +3 more
core  

Deep Multi-View Spatial-Temporal Network for Taxi Demand Prediction

open access: yes, 2018
Taxi demand prediction is an important building block to enabling intelligent transportation systems in a smart city. An accurate prediction model can help the city pre-allocate resources to meet travel demand and to reduce empty taxis on streets which ...
Gong, Pinghua   +8 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Short-Term Traffic Flow Reliability Prediction Method considering Traffic Safety [PDF]

open access: yesMathematical Problems in Engineering, 2020
With the rapid development and application of intelligent traffic systems, traffic flow prediction has attracted an increasing amount of attention. Accurate and timely traffic flow information is of great significance to improve the safety of transportation. To improve the prediction accuracy of the backward-propagation neural network (BPNN) prediction
Shaoqian Li   +3 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

MF-TCPV: A Machine Learning and Fuzzy Comprehensive Evaluation-Based Framework for Traffic Congestion Prediction and Visualization

open access: yesIEEE Access, 2020
A framework for traffic congestion prediction and visualization based on machine learning and Fuzzy Comprehensive Evaluation named MF-TCPV is proposed in this paper.
Leixiao Li   +4 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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