Results 231 to 240 of about 30,933 (313)

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Scalable architecture for autonomous malware detection and defense in software-defined networks using federated learning approaches. [PDF]

Sci Rep
Ranpara R, Patel SK, Kumar OP, Al-Zahrani FA.   +3 more
europepmc   +1 more source

Traffic-Rule-Compliant Trajectory Repair via Satisfiability Modulo Theories and Reachability Analysis

Yuanfei Lin, Z. Xing, X. Han, Matthias Althoff   +3 more
openalex   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Adolescent road safety: pedestrian behavior in ADHD and typically developing groups. [PDF]

BMC Psychol
Doerr E, Baldassa A, Capodieci A, Gastaldi M, Meneghetti C, Muffato V, Orsini F, Rossi R, Tagliabue M, Carretti B.   +9 more
europepmc   +1 more source

Rules and algorithms for an Advanced Traffic Management System

, 1999
David Schindl, T. Gauglhofer
openalex   +1 more source

Criminal law characteristics of the subjective side of crimes related to violations of traffic rules: the correlation of intent and negligence in the context of operating vehicles with automated driving systems

Anastasiya Feliksovna Dimovskih
openalex   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Entity relationship extraction method based on dependency parsing and graph neural networks. [PDF]

Sci Rep
Wei F, Liu X, Pan L, Zhao W, Shi G, Zeng Z, Jiao Y.   +6 more
europepmc   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source