A qualitative study to explore traffic police personnel perceptions towards road safety behaviour among young riders in Manipal, India. [PDF]
Sumit K+4 more
europepmc +1 more source
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo+3 more
wiley +1 more source
Translation of the Youth Attitude to Noise Scale and evaluation of Samoan university student attitudes towards recreational and environmental noise: A cross-sectional study to support the development of noise health promotion strategies. [PDF]
Kaspar A+5 more
europepmc +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
Research on intelligent energy management strategies for connected range-extended electric vehicles based on multi-source information. [PDF]
Zhai X, Liu H, Sun W, Su Z.
europepmc +1 more source
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan+4 more
wiley +1 more source
The pivotal role of software defined networks to safeguard against cyber attacks: a comprehensive review. [PDF]
Aljughaiman A, Almarri S.
europepmc +1 more source
The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu+17 more
wiley +1 more source
Road Traffic Gesture Autonomous Integrity Monitoring Using Fuzzy Logic. [PDF]
Ampadu KO, Huebner M.
europepmc +1 more source
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang+13 more
wiley +1 more source