Results 41 to 50 of about 30,933 (313)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cogent Social Sciences, 2017 Road safety is a complex process that not only depends on technical and environmental improvements, but in a major part from human factors. In this sense, recent empirical studies have remarked the need to study the interaction between subject and laws ...
Francisco Alonso +3 more
doaj +1 more source
U-Space Utilisation of Airspace under Various Layer Function Assignments and Allocations
Drones, 2023 The interest in urban air mobility as a potential solution for urban congestion is steadily growing. Air operations in urban areas can present added complexity as compared with traditional air traffic management.
Andres Morfin Veytia +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Secure Collecting, Optimizing, and Deploying of Firewall Rules in Software-Defined Networks
IEEE Access, 2020 Firewalls are a fundamental element of network security systems with the ability to block network data traffic flows according to pre-defined rules.
Sunghwan Kim +3 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Maqasid al-Syari’ah dalam Penegakkan Hukum Lalu Lintas di Indonesia
Al-Istinbath: Jurnal Hukum Islam, 2021 The high number of traffic accidents in Indonesia occurred because the traffic law enforcement does not run optimally. This paper tried to explore the rules regarding the traffic that have been contained in the form of Law no.
B. Busriyanti
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source