Results 41 to 50 of about 195,073 (241)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Improved Traffic Sign Detection and Recognition Algorithm for Intelligent Vehicles

open access: yesSensors, 2019
Traffic sign detection and recognition are crucial in the development of intelligent vehicles. An improved traffic sign detection and recognition algorithm for intelligent vehicles is proposed to address problems such as how easily affected traditional ...
Jingwei Cao   +4 more
doaj   +1 more source

Equirectangular Image Data Detection, Segmentation and Classification of Varying Sized Traffic Signs: A Comparison of Deep Learning Methods

open access: yesSensors, 2023
There are known limitations in mobile omnidirectional camera systems with an equirectangular projection in the wild, such as momentum-caused object distortion within images, partial occlusion and the effects of environmental settings.
Heyang (Thomas) Li   +2 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability

open access: yesAdvanced Engineering Materials, EarlyView.
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner   +3 more
wiley   +1 more source

A TWO-STEP CLASSIFICATION APPROACH TO DISTINGUISHING SIMILAR OBJECTS IN MOBILE LIDAR POINT CLOUDS [PDF]

open access: yesISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017
Nowadays, lidar is widely used in cultural heritage documentation, urban modeling, and driverless car technology for its fast and accurate 3D scanning ability.
H. He   +3 more
doaj   +1 more source

Simultaneous Traffic Sign Detection and Boundary Estimation using Convolutional Neural Network

open access: yes, 2018
We propose a novel traffic sign detection system that simultaneously estimates the location and precise boundary of traffic signs using convolutional neural network (CNN).
Kim, Kang, Lee, Hee Seok
core   +1 more source

Traffic sign detection and tracking using robust 3D analysis [PDF]

open access: yes, 2012
In this paper we present an innovative technique to tackle the problem of automatic road sign detection and tracking using an on-board stereo camera. It involves a continuous 3D analysis of the road sign during the whole tracking process.
Arróspide Laborda, Jon   +3 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

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