Results 211 to 220 of about 405,436 (291)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

A mosaic of microclimates: biodiversity outcomes and wildlife habitat potential in large‐scale solar facilities

open access: yesBiological Reviews, EarlyView.
ABSTRACT The rapid global expansion of photovoltaic (PV) solar facilities, now comprising nearly 80% of the recent and projected growth of renewable electricity, represents one of the most significant land‐use changes of the 21st century. While PV facilities are critical for decarbonising energy systems, their large spatial footprint and infrastructure
Tom Armstrong   +4 more
wiley   +1 more source

Organizational Sensemaking Theory Perspective of Developing AI‐Driven Strategies for Sustainability Initiatives

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Although artificial intelligence (AI) is increasingly being touted to assist organizations, AI integration for sustainability efforts has been limited AND sporadic and tends to follow an ad hoc strategy. The existing literature therein focuses on the technological capabilities of AI, overlooking how organizations make sense of and ...
Amanda Balasooriya, Darshana Sedera
wiley   +1 more source

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