Results 231 to 240 of about 9,675,732 (304)

X-THREAT framework for adaptive and explainable deep learning-based minority-class and zero-day cyber threat detection. [PDF]

Sci Rep
Qaisarani SN, Badri SK, Khattak A, Alghazzawi DM, Alghamdi MY, Alkhozae M, Almakky A, Alhazmi RM, Asghar MZ.   +8 more
europepmc   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

A post-quantum verified self-healing framework for healthcare IoT systems: deep anomaly detection, severity estimation and risk-aware rollback to trusted checkpoints. [PDF]

Front Artif Intell
Mathew AT, Mani P.
europepmc   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Advanced security framework for 5G-SDN attack detection and mitigation using Affinity Cohesive Clustering and Improved Chaotic Walrus-Optimized Convolutional LSTM with Deep Dual Info-Varcoder. [PDF]

Front Artif Intell
R S, Rajkumar S.
europepmc   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

APATCP: programmable multi-controller framework for real-time detection and mitigation of complex TCP flooding attacks in SD-IoT networks. [PDF]

Sci Rep
Alyanbaawi A, Hassan A, Khashaba MM, Elkomy O, Rushdy E, El-Sayed A.   +5 more
europepmc   +1 more source

Federated ConvNeXt-swin temporal fusion network for malware and botnet detection in IoT systems. [PDF]

Sci Rep
Alsubaei FS, Almazroi AA, Ayub N.
europepmc   +1 more source

Explainable Intrusion and Anomaly Detection for IoT Sensor Networks Using Hybrid Feature Selection and Deep Autoencoder Learning. [PDF]

Sensors (Basel)
Ahmed U, Muhammad S, Choi J.
europepmc   +1 more source

Urban environmental exposure as a factor in adaptive neuromodulation: a conceptual framework. [PDF]

Front Hum Neurosci
Qamili A, Cenameri A.
europepmc   +1 more source