Results 121 to 130 of about 904,971 (330)

Migrant workers’ access to medical service providers in Pennsylvania

Journal of Migration and Health
The H-2A Temporary Agricultural Workers program brings hundreds of thousands of foreign workers into the United States to work in the agricultural sector each year.
Philip Decicco, Jaya Prakash, Erica Nelson, Gonzalo Martínez de Vedia, Hanni Stoklosa   +4 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Law Enforcement and Illegal Trafficking of Waste: Evidence from Italy [PDF]

, 2015
The illegal trafficking of waste has become one of the fastest growing areas of crime and one of the most lucrative industries among organized criminal activities, which has infiltrated both the Italian urban and hazardous waste management cycle.
GERMANI, Anna Rita, PERGOLIZZI, ANTONINO, REGANATI, FILIPPO   +2 more
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Screening for human trafficking among homeless young adults

Children and youth services review, 2019
Human trafficking is a public health issue affecting homeless young adults across the United States; however, screening tools for trafficking specifically for this population are lengthy and onerous.
M. Chisolm‐Straker, J. Sze, Julia Einbond, James White, Hanni M. Stoklosa   +4 more
semanticscholar   +1 more source

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda, Hyo‐Min Kim, Nicole Battaglia, Joshua Rong, Amy Tam, Enrique Gonzalez Saez‐Diez, Cornelius F. Boerkoel, Afshin Saffari, Vicente Quiroz, Luca Schierbaum, Zainab Zaman, Katerina Bernardi, Darius Ebrahimi‐Fakhari   +12 more
wiley   +1 more source

Reframing Human Trafficking: From a Criminal Justice Problem to a Social Justice Issue [PDF]

, 2018
Laws addressing human trafficking have been passed in all 50 U.S. states as well as at the federal level. Although laws serve an important function in establishing social norms against a behavior, they can also create a belief that it is the ...
Pfeffer, Rebecca
core   +1 more source

The roles of endomembrane trafficking in plant abiotic stress responses.

Journal of Integrative Plant Biology, 2019
Endomembrane trafficking is a fundamental cellular process in all eukaryotic cells and its regulatory mechanisms have been extensively studied. In plants, the endomembrane trafficking system needs to be constantly adjusted to adapt to the ever-changing ...
Xiangfeng Wang, Min Xu, Caiji Gao, Yonglun Zeng, Yong Cui, Wenjin Shen, Liwen Jiang   +6 more
semanticscholar   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Phagolysosomal Trafficking Assay [PDF]

BIO-PROTOCOL, 2014
Phagolysosomal trafficking is an important innate defense pathway that clears microbes by delivering them to lysosomes, the degradative compartment of the cell. Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, subverts this host defense mechanism by arresting maturation of the phagosome.
openaire   +3 more sources