Results 151 to 160 of about 810,781 (333)

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

open access: yesAdvanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente   +5 more
wiley   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

open access: yesAdvanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma   +5 more
wiley   +1 more source

An uncharacterized region within the N-terminus of mouse TMC1 precludes trafficking to plasma membrane in a heterologous cell line [PDF]

open access: gold, 2019
David Soler   +5 more
openalex   +1 more source

Sex Trafficking of Children in the United States: Overview and Issues for Congress [PDF]

open access: yes, 2015
[Excerpt] This report provides an overview of sex trafficking of children in the United States. It first conceptualizes the issue, discussing the victims and perpetrators involved.
Fernandes-Alcantara, Adrienne L   +2 more
core   +3 more sources

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Innate immunity and metal ion trafficking pathway perturbations in idiopathic Parkinson's disease and Tuberculosis: A comparative transcriptomics approach

open access: gold, 2021
George D. Vavougios   +6 more
openalex   +1 more source

The Economics of Child Trafficking [PDF]

open access: yes
In this paper, we highlight the economic effects of the existence of child trafficking. We show that the risk of child trafficking on the labor market acts as a deterrent to supply child labor, unless household survival is at stake.
Stéphane Pallage, Sylvain Dessy
core  

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

Sex trafficking of girls and women : Evidence from Anantapur district, Andhra Pradesh [PDF]

open access: yes
A crucial gap in the trafficking literature from India is the dearth of primary data and micro studies that could be used for vulnerability mapping of the source areas and addressing the identified risk factors.
U. Vindhya, V. Swathi Dev
core   +1 more source

Lopez v. Gonzales & Toledo-Flores v. United States: State Felony Drug Convictions Not Necessarily Aggravated Felonies Requiring Deportation [PDF]

open access: yes, 2007
The United States Courts of Appeals split over whether state felony drug convictions, which were punishable only as misdemeanors under federal law, constituted aggravated felonies under immigration law.
Wagner, Ryan
core   +1 more source

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