Results 161 to 170 of about 810,781 (333)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

open access: yesAdvanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer   +10 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

The Spread of Anti-Trafficking Policies - Evidence from a New Index [PDF]

open access: yes
We analyze the spread of policies dealing with international trafficking in human beings. Arguing that countries are unlikely to make independent choices, we identify pressure, externalities and learning or emulation as plausible diffusion mechanisms for
Axel Dreher   +2 more
core   +3 more sources

The Economic Drivers of Human Trafficking: Micro-Evidence from Five Eastern European Countries.. [PDF]

open access: yes
Human trafficking is a humanitarian problem of global scale, but quantitative research on the issue barely exists. This paper is a first attempt to explore the economic drivers of human trafficking and migrant exploitation using micro data. We argue that
Omar Mahmoud, Toman, Trebesch, Christoph
core  

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking

open access: green, 2013
Fumiaki Ogawa   +7 more
openalex   +2 more sources

Transnational Trafficking, Law Enforcement and Victim Protection: A Middleman Trafficker's Perspective [PDF]

open access: yes
We explore three hitherto poorly understood characteristics of the human trafficking market – the cross-border ease of mobility of traffickers, the relative bargaining strength of traffickers and final buyers, and the elasticity of buyers' demand.
Akee, Randall K. Q.   +3 more
core  

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