Results 211 to 220 of about 126,381 (308)

Prosaposin in CNS health and disease, metabolic stress and exercise adaptation. [PDF]

J Mol Med (Berl)
Taha HB, Zhu S, Wang E.
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Conceptualizing mental health service delivery for refugee and forcibly displaced communities: A scoping review of service models and frameworks for populations impacted by trauma or displacement. [PDF]

Psychol Trauma
Bunn M, Potocky M, Graunke M, Dumett Torres E, Yunez S, Farmer B, Weine S.   +6 more
europepmc   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Recommendations from Multi-Disciplinary Professionals for Survivor-Informed and Comprehensive Care for Human Trafficking Survivors. [PDF]

Healthcare (Basel)
Tsoi CM, Smith TB, Cutrer-Párraga E, Clayton D, Marshall JM, Mastny J.   +5 more
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

NDR2 regulates non-small cell lung cancer cell migration under starvation by supporting autophagosome biogenesis through LC3 and ATG9A regulation. [PDF]

Cell Death Discov
Biojout T, Bergot E, Taylor J, Leite Ferreira D, Colloc'h N, Riffet M, Elie N, Guyot M, Bazille C, Levallet J, Levallet G.   +10 more
europepmc   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Firearm-related violence in the Caribbean is a complex systemic issue: how do we move towards a solution? [PDF]

Lancet Reg Health Am
Sobers NP, Agard J, Norville K, Fabre AS, Florquin N, Joseph C, Joseph M, Garcia-Joseph M, King R, Toppin PJ, Wong H, Anderson SG.   +11 more
europepmc   +1 more source

Giant Switchable Remanent Polarization and Photocurrent in Ferroelectric Thin Film Photomemristor for In Situ Training

Advanced Science, EarlyView.
The device exhibits excellent ferroelectric performance and significant photoelectric response. It can adapt to light stimuli of varying power and wavelengths while achieving a stable and tunable photovoltaic response state. Moreover, the device can utilize photoconductive states of different directions and magnitudes to achieve pattern classification ...
Zhen Zhao, Chengze Sun, Zhijin Duo, Yue Hou, Zhanfeng Wang, Jikang Xu, Ziye Li, Fu Wang, Pengfei Li, Ying Liu, Yongqing Jia, Kangbo Zhao, Jia Wu, Biao Yang, Weifeng Zhang, Weidong Sun, Jiacheng Wang, Jinxia Liu, Junfeng Yu, Xiang Ying, Jianxin Guo, Xiaobing Yan   +21 more
wiley   +1 more source